Experimental and clinical research focused on structural heart disease and diseases of the pulmonary circulation. Particular expertise within transcatheter LAA closure in atrial fibrillation, PFO closure, acute pulmonary embolism and chronic thromboembolic pulmonary hypertension.
The hypertension research group focus on mechansims and treatment possibilities in resistent essential hypertension and hypertension related to chronic kidney diseases. We are especially interested in the role of large artery stiffness and structural abnormalities of the resistance circulation.
We develop clinical relevant animals models simulating critical illness. This allows for a better understanding of the underlying pathophysiology. Furthmore, using these animals models the efficacy, safety, and mechanisms of novel interventions can be tested before transition to human studies.
Our research group use Danish nationwide databases to study the influence of coronary artery disease with a primary focus on diabetes and antithrombotic medications. Our aim is to improve our understanding of the interplay between coronary artery disease, co-morbidities and medications.