We develop clinical relevant animals models simulating critical illness. This allows for a better understanding of the underlying pathophysiology. Furthmore, using these animals models the efficacy, safety, and mechanisms of novel interventions can be tested before transition to human studies.
Experimental and clinical research focused on structural heart disease and diseases of the pulmonary circulation. Particular expertise within transcatheter LAA closure in atrial fibrillation, PFO closure, acute pulmonary embolism and chronic thromboembolic pulmonary hypertension.
Our research group use Danish nationwide databases to study the influence of coronary artery disease with a primary focus on diabetes and antithrombotic medications. Our aim is to improve our understanding of the interplay between coronary artery disease, co-morbidities and medications.
The hypertension research group focus on mechansims and treatment possibilities in resistent essential hypertension and hypertension related to chronic kidney diseases. We are especially interested in the role of large artery stiffness and structural abnormalities of the resistance circulation.
Our research aims to improve patient outcomes and delivery of patient-centered care after cardiac surgery. We lead and participate in multiple clinical trials as well as large, clinical registry-based studies. Read more at www.ctvs.au.dk
My research focus on understanding the clinical epidemiology of thrombosis and bleeding disorders e.g. disseminated intravascular coagulation, with particular attention to occurrence, prevention, role of biomarkers, treatment, risk factors, and prognosis.
Our research focuses on experimental cardiac surgery and biomechanical evaluation of different surgical techniques and devices, especially aortic valve repair with aortic rings. We also specialize in development of medical devices for cardiac surgery.
Read more at clin.au.dk/ctvs.