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Department of Clinical Medicine

Cardiothoracic and Vascular Surgery

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Arlander, B. A., Heiberg, J., Ringgaard, S., Sørensen, M. M., Redington, A. & Hjortdal, V. E. (2017). Impaired cardiac output during exercise in adults operated for ventricular septal defect in childhood: a hitherto unrecognised pathophysiological response. Cardiology in the Young, 27(8), 1591-1598. https://doi.org/10.1017/S1047951117000877

Heiberg, J., Nyboe, C. & Hjortdal, V. E. (2017). Impaired ventilatory efficiency after closure of atrial or ventricular septal defect. Scandinavian Cardiovascular Journal, 51(4), 221-227. https://doi.org/10.1080/14017431.2017.1326623

Larsen, S. H., Olsen, M., Emmertsen, K. & Hjortdal, V. E. (2017). Interventional Treatment of Patients With Congenital Heart Disease: Nationwide Danish Experience Over 39 Years. Journal of the American College of Cardiology, 69(22), 2725-2732. https://doi.org/10.1016/j.jacc.2017.03.587

Thorup, L., Simonsen, U., Grimm, D. & Hedegaard, E. R. (2017). Ivabradine: Current and Future Treatment of Heart Failure. Basic & Clinical Pharmacology & Toxicology, 121(2), 89-97. https://doi.org/10.1111/bcpt.12784

Clemmensen, T. S., Eiskjær, H., Løgstrup, B. B., Ilkjær, L. B. & Poulsen, S. H. (2017). Left ventricular global longitudinal strain predicts major adverse cardiac events and all-cause mortality in heart transplant patients. The Journal of Heart and Lung Transplantation, 36(5), 567-576. https://doi.org/10.1016/j.healun.2016.12.002

Peters, C. D., Kjaergaard, K. D., Nielsen, C. H., Christensen, K. L., Bibby, B. M., Jensen, J. D. & Jespersen, B. (2017). Long-term effects of angiotensin II blockade with irbesartan on inflammatory markers in hemodialysis patients: A randomized double blind placebo controlled trial (SAFIR study). Hemodialysis International, 21(1), 47–62 . https://doi.org/10.1111/hdi.12436

Karunanithi, Z., Nyboe, C. & Hjortdal, V. E. (2017). Long-Term Risk of Atrial Fibrillation and Stroke in Patients With Atrial Septal Defect Diagnosed in Childhood. The American Journal of Cardiology, 119(3), 461-465. https://doi.org/10.1016/j.amjcard.2016.10.015

Olsson, C., Ahlsson, A., Fuglsang, S., Geirsson, A., Gunn, J., Hansson, E. C., Hjortdal, V., Jarvela, K., Jeppsson, A., Mennander, A., Nozohoor, S., Wickbom, A., Zindovic, I. & Gudbjartsson, T. (2017). Medium-term survival after surgery for acute Type A aortic dissection is improving. European Journal of Cardio-Thoracic Surgery, 52(5), 852-857. https://doi.org/10.1093/ejcts/ezx302

Pilegaard, H. & Licht, P. B. (2017). Minimal Invasive Repair of Pectus Excavatum and Carinatum. Thoracic Surgery Clinics, 27(2), 123-131. https://doi.org/10.1016/j.thorsurg.2017.01.005

Perinpanayagam, M., Larsen, S. H., Emmertsen, K., Møller, M. B. & Hjortdal, V. E. (2017). Nineteen Years of Adult Congenital Heart Surgery in a Single Center. World Journal for Pediatric and Congenital Heart Surgery, 8(2), 182-188. https://doi.org/10.1177/2150135116682454

Skov, S. N., Blome, O., Noor, M. A. & Johansen, P. A. (2017). Novel Technique for Optical Strain Measurements on the Mitral Valve Anterior Leaflet. In Summer Biomechanics, Bioengineering and Biotransport Conference 2017 (Vol. 1, pp. 1113-1115)

Rønholt, K. & Iversen, L. (2017). Old and New Biological Therapies for Psoriasis. International Journal of Molecular Sciences (Online), 18(11), Article 2297. https://doi.org/10.3390/ijms18112297

Jaroszewski, D. E., Gustin, P. J., Haecker, F.-M., Pilegaard, H., Park, H. J., Tang, S.-T., Li, S., Yang, L., Uemura, S., De Campos, J. R. M., Obermeyer, R., Frantz, F. W., Torre, M., McMahon, L., Hebra, A., Chu, C.-C., Phillips, J. D., Notrica, D. M., Messineo, A. ... Yüksel, M. (2017). Pectus excavatum repair after sternotomy: the Chest Wall International Group experience with substernal Nuss bars. European Journal of Cardio-Thoracic Surgery, 52(4), 710-717. https://doi.org/10.1093/ejcts/ezx221

Heiberg, J., Nyboe, C. & Hjortdal, V. E. (2017). Permanent chronotropic impairment after closure of atrial or ventricular septal defect. Scandinavian Cardiovascular Journal, 51(5), 271-276. https://doi.org/10.1080/14017431.2017.1337216

Holmboe, S., Andersen, A., Vibjerg Jensen, R., Kimose, H. H., Ilkjær, L. B., Shen, L., Clapp, L. H. & Nielsen-Kudsk, J. E. (2017). Prostacyclins have no direct inotropic effect on isolated atrial strips from the normal and pressure-overloaded human right heart. Pulmonary Circulation, 7(2), 339-347. https://doi.org/10.1177/2045893217691532

Tang, M., Fenger-Eriksen, C., Wierup, P., Greisen, J., Ingerslev, J., Hjortdal, V. E. & Sørensen, B. (2017). Rational and timely haemostatic interventions following cardiac surgery - coagulation factor concentrates or blood bank products. Thrombosis Research, 154, 73-79. https://doi.org/10.1016/j.thromres.2017.04.004

Tambe, S. P., Kimose, H.-H., Greisen, J. R. & Jakobsen, C.-J. (2017). Re-exploration due to bleeding is not associated with severe postoperative complications. Interactive Cardiovascular and Thoracic Surgery, 25(2), 233-240. https://doi.org/10.1093/icvts/ivx071

Lyager, D. M. R., Ilkjær, C., Skov, S. N., Tjørnild, M. J., Sørensen, A. V., Jensen, H., Hjortdal, V. E. & Nielsen, S. L. (2017). Regional Changes In Leaflet Coaptation Dynamics After Total Tricuspid Reconstruction. Annals of Thoracic Surgery, 104(2), 599-605. https://doi.org/10.1016/j.athoracsur.2016.11.063

Nielsen, E. A., Okumura, K., Sun, M., Hjortdal, V. E., Redington, A. N. & Friedberg, M. K. (2017). Regional septal hinge-point injury contributes to adverse biventricular interactions in pulmonary hypertension. Physiological Reports, 5(14), e13332. Article e13332. https://doi.org/10.14814/phy2.13332

Skov, S. N., Røpcke, D. M., Tjørnild, M. J., Ilkjær, C., Rasmussen, J., Nygaard, H., M Hasenkam, J., Jensen, M. O. & Nielsen, S. L. (2017). Remodeling Mitral Annuloplasty Ring Concept with Preserved Dynamics of Annular Height. Journal of Heart Valve Disease, 26(3), 295-303.

Korsholm, K., Andersen, A., Mellemkjær, S., Nielsen, D. V., Klaaborg, K. E., Ilkjær, L. B. & Nielsen-Kudsk, J. E. (2017). Results from more than 20 years of surgical pulmonary endarterectomy for chronic thromboembolic pulmonary hypertension in Denmark. European Journal of Cardio-Thoracic Surgery, 52(4), 704-709. https://doi.org/10.1093/ejcts/ezx182

Skov, S. N., Lyager, D. M. R., Tjørnild, M. J., Ilkjær, C., Rasmussen, J., Nygaard, H., Jensen, M. O. & Nielsen, S. L. (2017). Semi-rigid mitral annuloplasty rings improve myocardial stress adaptation compared to rigid rings: insights from in vitro and in vivo experimental evaluation†. European Journal of Cardio-Thoracic Surgery, 51(5), 836-843. Article ezw421. https://doi.org/10.1093/ejcts/ezw421

Lyager, D. M. R., Ilkjaer, C., Tjornild, M. J., Skov, S. N., Ringgaard, S., Hjortdal, V. E. & Nielsen, S. L. (2017). Small intestinal submucosa tricuspid valve tube graft shows growth potential, remodelling and physiological valve function in a porcine model†. Interactive Cardiovascular and Thoracic Surgery, 24(6), 918-924. https://doi.org/10.1093/icvts/ivx017

Sørensen, M. M., Heiberg, J. & Hjortdal, V. E. (2017). Small, unrepaired ventricular septal defects reveal poor exercise capacity compared with healthy peers: A prospective, cohort study. International Journal of Cardiology, 227, 631-634. https://doi.org/10.1016/j.ijcard.2016.10.086

Telinius, N., Majgaard, J. C., Mohanakumar, S., Pahle, E., Nielsen, J., Hjortdal, V., Aalkjær, C. & Boedtkjer, D. B. (2017). Spontaneous and Evoked Contractility of Human Intestinal Lymphatic Vessels. Lymphatic research and biology, 15(1), 17-22. https://doi.org/10.1089/lrb.2016.0039

Tang, M., Wierup, P., Rea, C. J., Ingerslev, J., Hjortdal, V. E. & Sørensen, B. (2017). Temporal changes in clot lysis and clot stability following tranexamic acid in cardiac surgery. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 28(4), 295-302. https://doi.org/10.1097/MBC.0000000000000595

Skov, M., de Paoli, F. V., Nielsen, O. B. & Pedersen, T. H. (2017). The anti-convulsants lacosamide, lamotrigine and rufinamide reduce myotonia in isolated human and rat skeletal muscle. Muscle & Nerve, 56(1), 136-142. https://doi.org/10.1002/mus.25452

Skov, S. N., Lyager, D. M. R., Tjørnild, M. J., Ilkjær, C., Rasmussen, J., Nygaard, H., Jensen, M. Ø. J. & Nielsen, S. L. (2017). The effect of different mitral annuloplasty rings on valve geometry and annular stress distribution†. Interactive Cardiovascular and Thoracic Surgery, 24(5), 683-690. https://doi.org/10.1093/icvts/ivx004

Musa, N. L., Hjortdal, V., Zheleva, B., Murni, I. K., Sano, S., Schwartz, S. & Staveski, S. L. (2017). The global burden of paediatric heart disease. Cardiology in the Young, 27(S6), S3-S8. https://doi.org/10.1017/S1047951117002530

Agger, P., Gleesborg, D. M., Ramsing, M. & Hjortdal, V. (2017). The human fetal right ventricular myocardium appears without a sub-epicardial base-apex oriented layer of myocytes. Pediatric Research, 81(3), 396-397. https://doi.org/10.1038/pr.2016.248

Grøndahl, C., Pedersen, T. A. L. & Hjortdal, V. E. (2017). The Medium-Term Effects of Treatment for Mild Aortic Recoarctation. World Journal for Pediatric and Congenital Heart Surgery, 8(1), 55-61. https://doi.org/10.1177/2150135116668334

Adelborg, K., Horváth-Puhó, E., Schmidt, M., Munch, T., Pedersen, L., Nielsen, P. H., Bøtker, H. E. & Toft Sørensen, H. (2017). Thirty-Year Mortality After Coronary Artery Bypass Graft Surgery: A Danish Nationwide Population-Based Cohort Study. Circulation: Cardiovascular Quality and Outcomes, 10(5), e002708. Article e002708. https://doi.org/10.1161/CIRCOUTCOMES.116.002708

Søvsø Szocska Hansen, E., Pedersen, S. F., Pedersen, S. B., Bøtker, H. E. & Kim, W. Y. (2017). Validation of Contrast Enhanced Cine Steady-State Free Precession and T2-Weigthed CMR for Assessment of Ischemic Myocardial Area- At-Risk. In ISMRM 2017 Proceedings

Christensen, T. D., Vad, H., Pedersen, S., Licht, P. B., Nybo, M., Hornbech, K., Zois, N. E. & Hvas, A.-M. (2017). Video-assisted Thoracoscopic surgery (VATS) lobectomy for lung cancer does not induce a procoagulant state. Thrombosis Journal, 15(1), 29. Article 29. https://doi.org/10.1186/s12959-017-0152-2

Heide-Jørgensen, S., Kumaran Krishna, S., Taborsky, J., Bechsgaard, T. K., Zegdi, R. & Johansen, P. (2016). A Novel Method for Optical High Spatiotemporal Strain Analysis for Transcatheter Aortic Valves In Vitro. Journal of Biomechanical Engineering, 138(3), Article 034504. https://doi.org/10.1115/1.4032501

Lomholt, J. J., Jacobsen, E. B., Thastum, M. & Pilegaard, H. (2016). A prospective study on quality of life in youths after pectus excavatum correction. Annals of Cardiothoracic Surgery, 5(5), 456-465. https://doi.org/10.21037/acs.2016.08.02

Udholm, S., Sørensen, M. M., Pilegaard, H. & Hjortdal, V. E. (2016). Cardiac function in adults following minimally invasive repair of pectus excavatum†. Interactive Cardiovascular and Thoracic Surgery, 22(5), 525-529. https://doi.org/10.1093/icvts/ivw007

Hansen, E. S. S., Pedersen, S. F., Pedersen, S. B., Kjærgaard, U., Schmidt, N. H., Bøtker, H. E. & Kim, W. Y. (2016). Cardiovascular MR T2-STIR imaging does not discriminate between intramyocardial haemorrhage and microvascular obstruction during the subacute phase of a reperfused myocardial infarction. Open Heart, 3(1), e000346. https://doi.org/10.1136/openhrt-2015-000346

Riis, J. L., Vestergaard, C., Deleuran, M. S. & Olsen, M. (2016). Childhood atopic dermatitis and risk of attention deficit/hyperactivity disorder: A cohort study. Journal of Allergy and Clinical Immunology, 138(2), 608-610. https://doi.org/10.1016/j.jaci.2016.01.027

Hyldebrandt, J. A., Støttrup, N. B., Frederiksen, C. A., Heiberg, J., Dupont Birkler, R. I., Johannsen, M., Schmidt, M. R. & Ravn, H. B. (2016). Citric Acid Cycle Metabolites Predict the Severity of Myocardial Stunning and Mortality in Newborn Pigs. Pediatric Critical Care Medicine, 17(12), e567-e574. https://doi.org/10.1097/PCC.0000000000000982

Matthiesen, N. B., Henriksen, T. B., Gaynor, J. W., Agergaard, P., Bach, C. C., Hjortdal, V. & Ostergaard, J. R. (2016). Congenital Heart Defects and Indices of Fetal Cerebral Growth in a Nationwide Cohort of 924,422 Liveborn Infants. Circulation, 133(6), 566-575. https://doi.org/10.1161/CIRCULATIONAHA.115.019089

Matthiesen, N. B., Henriksen, T. B., Agergaard, P., Gaynor, J. W., Bach, C. C., Hjortdal, V. E. & Østergaard, J. R. (2016). Congenital Heart Defects and Indices of Placental and Fetal Growth in a Nationwide Study of 924 422 Liveborn Infants. Circulation, 134(20), 1546-1556. https://doi.org/10.1161/CIRCULATIONAHA.116.021793

Matthiesen, N. B., Agergaard, P., Henriksen, T. B., Bach, C. C., Gaynor, J. W., Hjortdal, V. & Østergaard, J. R. (2016). Congenital Heart Defects and Measures of Fetal Growth in Newborns with Down Syndrome or 22q11.2 Deletion Syndrome. The Journal of Pediatrics, 175, 116-122.e4. https://doi.org/10.1016/j.jpeds.2016.04.067

Nielsen, S. L. (2016). Current Status of Transcatheter Mitral Valve Repair Therapies - From Surgical Concepts Towards Future Directions. Scandinavian Cardiovascular Journal, 50(5-6), 367-376. https://doi.org/10.1080/14017431.2016.1248482

Pedersen, C. M., Mellemkjær, S., Nielsen-Kudsk, J. E., Korsholm, K., Andersen, G. & Ilkjær, L. B. (2016). Diagnosis and treatment of chronic thromboembolic pulmonary hypertension in Denmark. Ugeskrift for Læger, 178(50).

Nielsen, E. A., Sun, M., Honjo, O., Hjortdal, V. E., Redington, A. N. & Friedberg, M. K. (2016). Dual Endothelin Receptor Blockade Abrogates Right Ventricular Remodeling and Biventricular Fibrosis in Isolated Elevated Right Ventricular Afterload. PLoS One, 11(1), e0146767. Article e0146767. https://doi.org/10.1371/journal.pone.0146767

Nielsen, P. H., Hjortdal, V., Modrau, I. S., Jensen, H., Kimose, H.-H., Terp, K., Poulsen, S. H., Smerup, M. & Nielsen, S. L. (2016). Durability after aortic valve replacement with the Mitroflow versus the Perimount pericardial bioprosthesis: a single-centre experience in 2393 patients†. European Journal of Cardio-Thoracic Surgery, 49(6), 1705-1710. https://doi.org/10.1093/ejcts/ezv432

Larsen, T. B., Skjøth, F., Grove, E. L., Nielsen, P. B. & Christensen, T. D. (2016). Effectiveness of self-managed oral anticoagulant therapy in patients with recurrent venous thromboembolism. A propensity-matched cohort study. Thrombosis and Haemostasis, 116(3), 524-529. https://doi.org/10.1160/TH16-02-0088

Ilkjær, C., Møller, M. B., Lauridsen, M. H., Ilkjær, S. & Hjortdal, V. E. (2016). Effekt af julenisserier på humøret blandt læger - et randomiseret, blindet interventionsstudie. Ugeskrift for Læger, 177(25), 2357-2360.

Jensen, B. T., Laustsen, S., Jensen, J. B., Borre, M. & Petersen, A. K. (2016). Exercise-based pre-habilitation is feasible and effective in radical cystectomy pathways-secondary results from a randomized controlled trial. Supportive Care in Cancer, 24(8), 3325–3331. https://doi.org/10.1007/s00520-016-3140-3

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Department of Cardiothoracic and Vascular Surgery