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Neurology Research Group
Neurology is increasingly adapting biomarkers to support diagnosis, predict prognosis, and support treatment decisions. In our research group, we focus on neurological biomarkers with a particular emphasis on translating them from the research setting into clinical use. We expect to advance the field, ultimately improving patient care and optimizing the use of healthcare resources. Our research is conducted in the cross field between clinical biochemistry and epidemiology by combining local and large-scale nationwide clinical and biobank data with primary data collection. In the lab, we use advanced immunometric techniques, such as ultra-sensitive digital immunoassays (Simoa, Quanterix), automated electrochemiluminescence immunoassays, and enzyme-linked immunosorbent assays (ELISA).
Main research interests are:
| Selected biomarkers of interest (CSF or blood) | |
Tau (e.g. phosphorylated tau217 and other isoforms) | Alzheimer´s disease |
| Beta-amyloid (1-42) | Alzheimer´s disease |
| GFAP | Brain injury, stroke, neurodegenerative diseases |
| NfL | Brain injury, stroke, neurodegenerative diseases, multiple sclerosis, amyotrophic lateral sclerosis, polyneuropathy |
| CAF | Amyotrophic lateral sclerosis |
| ARAb | Myasthenia gravis |
| NSE | Brain injury, cardiac arrest |
Tina Parkner
Clinical Associate Professor,
MD, PhD
Cindy Søndersø Knudsen
MSc
Kristina Laugesen
MD, PhD
Jacob Rudjord Therkildsen
MD, PhD
Holger Jon Møller
Professor, MD, PhD
Katrine Bremer
Laboratory Technician
Niels Okkels, MD, PhD, Department of Neurology, Aarhus University Hospital
Hanne Gottrup, MD, PhD, Department of Neurology, Aarhus University Hospital
Per Borghammer, MD, PhD, Professor, Department of Nuclear Medicine & PET, Aarhus University Hospital
Christian Erikstrup, MD, PhD, Professor, Department of Clinical Immunology, Aarhus University Hospital
Jesper Helbo Storgaard, MD, PhD student, Department of Neurology, Aarhus University Hospital
Henning Andersen, MD, PhD, Professor, Department of Neurology, Aarhus University Hospital
Silje Hovden Christensen
MD, PhD student