At Department of Renal Medicine biomarkers of excessive immunosuppression such as EBV are explored to prevent posttransplant cancer and infections. Experimental pig models are available for prevention of ischaemia reperfusion injury, e.g. using mesenchymal stromal cells and kidney machine perfusion.
We want to understand the underlying molecular mechanisms in chronic inflammatory skin diseases with a central focus on psoriasis. Our goal is to identify specific inflammatory factors and signaling pathways that are essential to the disease pathogenesis, and to transform these findings into novel therapeutic strategies.
I study viral infections and human immune responses. I seek to explore adaptive and innate immune modulation and develop novel immunotherapy treatments. I work on implementing novel treatments through clinical trials and to study virology and immunology in humanized mice and in primary cell culture.
The focus of my research is understanding differential susceptibility to severe infectious diseases in humans. We study the role of host genetics and immune responses in herpesvirus infections of the brain as well as influenza and COVID19 and use this knowledge to improve diagnosis, prophylaxis and treatment of patients.
Reseach focus: Clinical and epidemiologica aspects of hepatitis C. Project involving screening for hepatitis B and C among risk groups. As member of Guinea Bissau HIV study group we look improvement of the treatment cascade and diagnistics of opportunistic infections.
We investigate microbiological, clinical, and biochemical aspects of pharyngeal infections. Our vision is to clarify the significant pathogens associated with these infections and improve the medical and surgical treatment regimens.