Jensen, N. M., Vitic, Z., Antorini, M. R., Viftrup, T. B., Parkkinen, L.
& Jensen, P. H. (2025).
Abundant non-inclusion α-synuclein pathology in Lewy body-negative LRRK2-mutant cases.
Acta Neuropathologica,
149(1), Article 41.
https://doi.org/10.1007/s00401-025-02871-w
Theologidis, V., Ferreira, S. A., Jensen, N. M., Gomes Moreira, D., Ahlgreen, O. A., Hansen, M. W., Rosenberg, E. D., Richner, M., Faress, I., Gram, H., Jensen, P. H., Borghammer, P., Nyengaard, J. R., Romero-Ramos, M., Vægter, C. B., van de Berg, W. D. J.
, Van Den Berge, N. & Jan, A. (2025).
Bradykinesia and postural instability in a model of prodromal synucleinopathy with α-synuclein aggregation initiated in the gigantocellular nuclei.
Acta Neuropathologica Communications,
13(1), 32. Article 32.
https://doi.org/10.1186/s40478-025-01948-7
Hvingelby, V. S., Terkelsen, M. H., Johnsen, E. L., Møller, M., Danielsen, E. H., Henriksen, T.
, Glud, A. N., Tai, Y. F.
, Møller Andersen, A. S., Knudsen, A.-L., Meier, K., Horsager, J., Okkels, N., Sørensen, J. C. H., Borghammer, P., Moro, E.
& Pavese, N. (2025).
Cholinergic patterns correlate with dopamine medication ON freezing of gait in Parkinson's disease.
Brain : a journal of neurology,
148(12), 4508-4518. Article awaf231.
https://doi.org/10.1093/brain/awaf231
Bøgh, N., Aastrup, M., Mortensen, J. K., Gottrup, H., Blicher, J. U.
, Borghammer, P., Kristensen, M. H., Hansen, E. S. S., Vaeggemose, M. & Laustsen, C. (2025).
Comparison of Deuterium Metabolic Imaging with FDG PET in Alzheimer Disease.
Radiology,
315(1), e241808. Article e241808.
https://doi.org/10.1148/radiol.241808
Labrador-Espinosa, M. A., Silva-Rodriguez, J.
, Okkels, N., Muñoz-Delgado, L.
, Horsager, J., Castro-Labrador, S., Franco-Rosado, P., Castellano-Guerrero, A. M., Iglesias-Camacho, E., San-Eufrasio, M., Macías-García, D., Jesús, S., Adarmes-Gómez, A., Ojeda-Lepe, E., Carrillo, F., Martín-Rodríguez, J. F., Roldan Lora, F., García-Solís, D.
, Borghammer, P. ... Grothe, M. J. (2025).
Cortical hypometabolism in Parkinson’s disease is linked to cholinergic basal forebrain atrophy.
Molecular Psychiatry,
30(6), 2372-2380. Article 44.
https://doi.org/10.1038/s41380-024-02842-9
Baun, A. M., Iranzo, A.
, Terkelsen, M. H., Stokholm, M. G., Stær, K., Serradell, M.
, Otto, M., Svendsen, K. B., Garrido, A., Vilas, D., Santamaria, J.
, Møller, A., Gaig, C.
, Brooks, D. J., Borghammer, P., Tolosa, E.
, Eskildsen, S. F. & Pavese, N. (2025).
Cuneus atrophy and Parkinsonian phenoconversion in cognitively unimpaired patients with isolated REM sleep behavior disorder.
Journal of Neurology,
272(1), Article 59.
https://doi.org/10.1007/s00415-024-12762-x
Rohde, C.
, Langeskov-Christensen, M., Jørgensen, L. B., Borghammer, P. & Østergaard, S. D. (2025).
Depression preceding and following the diagnosis of Parkinson's disease and Lewy body dementia.
General Psychiatry,
38(6), Article e102405.
https://doi.org/10.1136/gpsych-2025-102405
Joza, S., Delva, A., Tremblay, C., Vo, A., Filiatrault, M., Tweedale, M., Gagnon, J. F., Postuma, R. B., Dagher, A., Klein, J., Hu, M., Dusek, P., Marecek, S., Varga, Z., Taylor, J. P., O'Brien, J. T., Firbank, M., Thomas, A., Donaghy, P. C. ... ICEBERG Study Group (2025).
Distinct brain atrophy progression subtypes underlie phenoconversion in isolated REM sleep behaviour disorder.
EBioMedicine,
117, Article 105753.
https://doi.org/10.1016/j.ebiom.2025.105753
Filiatrault, M., Ayral, V., Tremblay, C., Haddad, C., Daneault, V., Pastor-Bernier, A., Gagnon, J. F., Postuma, R. B., Dušek, P., Mareček, S., Varga, Z., Klein, J. C., Hu, M. T., Arnulf, I., Dodet, P., Vidailhet, M., Corvol, J. C., Lehéricy, S., Lewis, S. ... ICEBERG Study Group (2025).
Estrogen-related receptor gene expression associates with sex differences in cortical atrophy in isolated REM sleep behavior disorder.
Nature Communications,
16(1), Article 9016.
https://doi.org/10.1038/s41467-025-63829-w
Schmidt, S. I., Okarmus, J., Madsen, D. A., Hansen, J. S.
, Gregersen, E., Gram, H., Winkelmann, L. S., Oliveira, A. S., Heon-Roberts, R., Ryan, B. J., Freude, K., Blaabjerg, M.
, Jensen, P. H. & Meyer, M. (2025).
Formation of seeding-competent α-synuclein aggregates in parkin-deficient iPSC-derived human neurons.
npj Parkinson's Disease ,
11(1), Article 180.
https://doi.org/10.1038/s41531-025-01038-4
Andersen, N. H., Borghammer, P., Doppler, K.
, Gottrup, H., Knudsen, K., Kuzkina, A.
, Van Den Berge, N., Otto, M. & Terkelsen, A. J. (2025).
Idiopathic polyneuropathy with neurogenic autonomic failure – an early manifestation of Lewy body disease? a case report.
BMC Neurology,
25(1), Article 432 .
https://doi.org/10.1186/s12883-025-04414-y
Gugu, M., Acharya, S., Pira, D., Poletti, S., di Flora, A., Saksida, T., Pilipenko, V.
, Romero-Ramos, M., Marino, F., Muñoz Delgado, L., Nikolovski, N., Gursoy Ozdemir, Y., Lawson, D., Comi, C. & Figueira, I. (2025).
IMMUnity Unveiled: A Translational NETwork for tackling PARKinson's Disease – IMMUPARKNET.
Open Research Europe,
4, Article 119.
https://doi.org/10.12688/openreseurope.17547.2
Faisal Mohamad, N.
, Koch, K. U., Aanerud, J., Meier, K., Mikkelsen, I. K., Espelund, U. S., Eriksen, C. F., Juul, N., Alstrup, K. B., Jespersen, B., Fries, L. M.
, Tankisi, A., Dyrskog, S., Cortnum, S. O. S., Sindby, A. K.
, Borghammer, P., Tolbod, L. P., Meng, L.
, Korshoej, A. R. & Rasmussen, M. (2025).
Impact of norepinephrine versus phenylephrine on brain circulation, organ blood flow and tissue oxygenation in anaesthetised patients with brain tumours: study protocol for a randomised controlled trial.
BMJ Open,
15(3), Article e095172.
https://doi.org/10.1136/bmjopen-2024-095172
Klæstrup, I. H., Reinert, L. S., Ferreira, S. A., Lauritsen, J., Toft, G. U., Gram, H., Jensen, P. H., Paludan, S. R. & Romero-Ramos, M. (2026).
Lack of functional STING modulates immunity but does not protect dopaminergic neurons in the alpha-synuclein pre-formed fibrils Parkinson's disease mouse model.
npj Parkinson's Disease ,
12(1), Article 17. Advance online publication.
https://doi.org/10.1038/s41531-025-01228-0
Kivistö, V., Englert, B., Tuimala, J., Kok, E. H., Puttonen, H., Raunio, A., Karhunen, P., Lehtinen, M. K.
, Borghammer, P., Ahvenainen, E., Colangelo, K., Savola, S., Tanskanen, M., Kaivola, K., Tienari, P. J., Kumar, D., Paetau, A., Tynninen, O., Mäyränpää, M. I. ... Myllykangas, L. (2025).
Myocardial sympathetic distal axon loss in subjects with Lewy pathology: an artificial intelligence-based histopathological analysis.
Alzheimer's & dementia : the journal of the Alzheimer's Association,
21(Suppl 7), e108548.
https://doi.org/10.1002/alz70861_108548
Kivistö, V., Englert, B., Tuimala, J., Kok, E., Puttonen, H., Raunio, A., Karhunen, P. J., Lehtinen, M. K.
, Borghammer, P., Ahvenainen, E., Colangelo, K., Savola, S., Tanskanen, M., Kaivola, K., Tienari, P. J., Kumar, D., Paetau, A., Tynninen, O., Mäyränpää, M. I. ... Myllykangas, L. (2025).
Myocardial sympathetic distal axon loss in subjects with Lewy pathology in three autopsy cohorts.
Acta Neuropathologica,
150(1), 11. Article 11.
https://doi.org/10.1007/s00401-025-02918-y
Nielsen, J., Pedersen, J. N., Kleijwegt, G.
, Nowak, J. S., Nami, F., Johansen, C., Sassetti, E.
, Berg, B. B., Lyngsø, N. M., Brøchner, B. H., Holm Carlson, J.
, Simonsen, A. J., Pallisgaard Olsen, W., Simonsen, B. W., Mikkelsen, J. H., Sereika-Bejder, V.
, Lauritsen, J. A., Merrild, K. F., Malle, M. G. ... Otzen, D. E. (2025).
Nanobodies raised against the cytotoxic α-synuclein oligomer are oligomer-specific and promote its cellular uptake.
npj biosensing,
2, Article 23.
https://doi.org/10.1038/s44328-025-00042-1
Backman, E. A., Gardberg, M., Luntamo, L., Peurla, M., Vahlberg, T.
, Borghammer, P., Stefanova, N., Wenning, G. & Kaasinen, V. (2025).
Nigral Neuroinflammation and Dopaminergic Neurons in Parkinson's Disease and Atypical Parkinsonisms.
Annals of Neurology,
97(6), 1096-1109.
https://doi.org/10.1002/ana.27202
Hansen, F. O., Knudsen, K., Damholdt, M. F., Bek, T., Borghammer, P. & Okkels, N. (2025).
Non-motor asymmetry and dopamine degeneration in Parkinson's disease.
Brain Communications,
7(1), Article fcaf002.
https://doi.org/10.1093/braincomms/fcaf002
Christiansen, J. R., Ferreira, S. A., Szymkowski, D. E., Jakobsson, J., Tansey, M. G.
& Romero-Ramos, M. (2025).
Peripherally administered TNF inhibitor is not protective against α-synuclein-induced dopaminergic neuronal death in rats.
Neurobiology of Disease,
206, Article 106803.
https://doi.org/10.1016/j.nbd.2025.106803
Andersen, K. B., Krishnamurthy, A., Just, M. K., Van Den Berge, N., Skjærbæk, C., Horsager, J., Knudsen, K., Vogel, J. W., Toledo, J. B., Attems, J., Polvikoski, T., Saito, Y., Murayama, S.
& Borghammer, P. (2025).
Sympathetic and parasympathetic subtypes of body-first Lewy body disease observed in postmortem tissue from prediagnostic individuals.
Nature Neuroscience,
28(5), 925-936. Article 1255555.
https://doi.org/10.1038/s41593-025-01910-9
Ding, X., Lai, X., Klaestrup, I. H., Jensen, S. R. N., Nielsen, M. M., Thorsen, K., Romero-Ramos, M., Luo, Y., Lin, L., Reinert, L. S. & Paludan, S. R. (2025).
Temporally resolved single-cell RNA sequencing reveals protective and pathological responses during herpes simplex virus CNS infection.
Journal of Neuroinflammation,
22(1), Article 146.
https://doi.org/10.1186/s12974-025-03471-x
Munk, O. L., Rodell, A. B., Danielsen, P. B.
, Madsen, J. R., Sørensen, M. T.
, Okkels, N., Horsager, J., Andersen, K. B., Borghammer, P., Aanerud, J., Jones, J., Hong, I. & Zuehlsdorff, S. (2025).
Validation of a data-driven motion-compensated PET brain image reconstruction algorithm in clinical patients using four radiotracers.
EJNMMI Physics,
12(1), Article 11.
https://doi.org/10.1186/s40658-025-00723-w
da Silva, I. S., Cardoso, A. R.
, Reimer, L., König, A., van Riesen, C., Outeiro, T. F.
, Jensen, P. H. & Sales, M. G. F. (2025).
α-Synuclein plastic antibody applied to monitor monomeric structures and discriminate aggregated forms in human CSF.
Biosensors and Bioelectronics,
268, 116880. Article 116880.
https://doi.org/10.1016/j.bios.2024.116880