Find

Department of Clinical Medicine

Research Unit for Molecular Medicine (MMF)

Publications

Sort by: Date | Author | Title

Bie AS 2015. The mitochondrial chaperonin complex Hsp60/Hsp10: Identification of Hsp60 client proteins and investigations of a mutation in HSPE1. Health, Aarhus University.

Britze A , Palmfeldt J , Gregersen N , Ovesen T. 2014. 44-plex cytokine profile of cholesteatoma. Acta Oto-Laryngologica. 134(1):41-50. https://doi.org/10.3109/00016489.2013.844360

Sibbersen C , Lykke L , Gregersen N , Jørgensen KA , Johannsen M. 2014. A cleavable azide resin for direct click chemistry mediated enrichment of alkyne-labeled proteins. Chemical Communications. 50(81):12098-12100. https://doi.org/10.1039/c4cc05246c

Bross P , Bie AS. 2014. A complex phenotype including infantile spasms and the developmental delay is associated with heterozygosity for a mutation in the mitochondrial co-chaperone Hsp10. Poster session presented at Euromit 2014, Tampere, Finland.

Skott M , Nørregaard R, Birke-Sørensen H, Palmfeldt J, Kwon T-H, Frøkiaer J, Nielsen S. 2014. Acute kidney injury in rats with or without pre-existing chronic kidney disease: cytokine/chemokine response. Nephrology. 19(7):410-9. https://doi.org/10.1111/nep.12263

Nochi Z , Andreasen C , Corydon TJ , Gregersen N. 2014. APPROACHES TO DECIPHERING THE BALANCE BETWEEN SURVIVAL AND DEATH MECHANISMS IN CELLS WITH MITOCHONDRIAL DYSFUNCTION. Poster session presented at Aarhus University Graduate School of Health, PhD Day 2014, Aarhus, Denmark.

Nochi Z , Gregersen N. 2014. APPROACHES TO DECIPHERING THE BALANCE BETWEEN SURVIVAL AND DEATH MECHANISMS IN CELLS WITH MITOCHONDRIAL DYSFUNCTION. Poster session presented at Euromit 2014, Tampere, Finland.

Fernandez-Guerra P 2014. Cellular characterization of human dermal fibroblasts, focus on mitochondria and maple syrup urine disease: PhD dissertation. Master of Public health, Aarhus Universitet. 214 p.

Cornelius N , Corydon TJ , Gregersen N , Olsen RKJ. 2014. Cellular consequences of oxidative stress in riboflavin responsive multiple acyl-CoA dehydrogenation deficiency patient fibroblasts. Human Molecular Genetics. https://doi.org/10.1093/hmg/ddu146

Rohde MC , Corydon TJ , Hansen J , Pedersen CB , Schmidt SP , Gregersen N , Banner J. 2014. Characteristics of human infant primary fibroblast cultures from Achilles tendons removed post-mortem. Forensic Science International. 234:149-53. https://doi.org/10.1016/j.forsciint.2013.11.007

Al-Saaidi R , Bross P. 2014. Do lamin A and lamin C have unique roles?. Chromosoma. https://doi.org/10.1007/s00412-014-0484-7

Al-Saaidi RA. 2014. Do lamin A and lamin C have unique roles?. Poster session presented at Gordon Research Conference , West Dover, United States.

Kristensen LS , Søes S , Hansen LL. 2014. ELMO3: a direct driver of cancer metastasis?. Cell Cycle. 13(16):2483-4. https://doi.org/10.4161/15384101.2014.947228

Henriques BJ, Lucas TG, Rodrigues JV, Frederiksen JH, Teixeira MS, Tiranti V, Bross P, Gomes CM. 2014. Ethylmalonic encephalopathy ETHE1 R163W/R163Q mutations alter protein stability and redox properties of the iron centre. PLOS ONE. 9(9):e107157. https://doi.org/10.1371/journal.pone.0107157

Britze A , Birkler RID , Gregersen N , Ovesen T , Palmfeldt J. 2014. Large-scale proteomics differentiates cholesteatoma from surrounding tissues and identifies novel proteins related to the pathogenesis. PLOS ONE. 9(8):e104103. https://doi.org/10.1371/journal.pone.0104103

Palmfeldt J , Fernandez-Guerra P , Birkler RID. 2014. Mass spectrometry protein quantification in maple syrup urine disease. [Pictures, Video and sound recordings (digital)].

Tonin AM, Amaral AU, Busanello EN, Gasparotto J, Gelain DP, Gregersen N, Wajner M. 2014. Mitochondrial bioenergetics deregulation caused by long-chain 3-hydroxy fatty acids accumulating in LCHAD and MTP deficiencies in rat brain: A possible role of mPTP opening as a pathomechanism in these disorders?. BBA General Subjects. https://doi.org/10.1016/j.bbadis.2014.06.011

Sahebekhtiari N , Bross P , Gregersen N , Palmfeldt J. 2014. MITOCHONDRIAL PROTEOME CHANGES IN ETHE1- DEFICIENT MICE: INDICATION OF METABOLIC IMBALANCE. Poster session presented at Aarhus University Graduate School of Health, PhD Day 2014, Aarhus, Denmark.

Cornelius N , Gregersen N, Tümer Z, Olsen RKJ. 2014. Oxidative stress and mitochondrial defect in neuromuscular disorders: source or symptoms?. In Oxidative Stress: Causes, Role in Diseases and Biological Effects. Nova Publishers.

Stødkilde-Jørgensen L , Palmfeldt J , Nilsson L , Carlsen IG , Wang Y , Nørregaard R , Frøkiær J. 2014. Proteomic identification of early changes in the renal cytoskeleton in obstructive uropathy. A J P: Renal Physiology (Online). 306(12). https://doi.org/10.1152/ajprenal.00244.2013

Edhager AV , Stenbroen V , Nielsen NS , Bross P , Olsen RKJ , Gregersen N , Palmfeldt J. 2014. Proteomic investigation of cultivated fibroblasts from patients with mitochondrial short-chain acyl-CoA dehydrogenase deficiency. Molecular Genetics and Metabolism. 111(3):360-368. https://doi.org/10.1016/j.ymgme.2014.01.007

Fernandez Guerra P , Birkler RID , Palmfeldt J , Bross P. 2014. PROTEOMICS AND CELLULAR OXIDATIVE STRESS STUDIES IN FIBROBLASTS FROM CLASSIC MAPLE SYRUP URINE DISEASE PATIENTS. Poster session presented at Aarhus University Graduate School of Health, PhD Day 2014, Aarhus, Denmark.

Fernández-Guerra P , Birkler RID, Merinero B, Ugarte M, Gregersen N, Rodríguez-Pombo P, Bross P , Palmfeldt J. 2014. Selected reaction monitoring as an effective method for reliable quantification of disease-associated proteins in maple syrup urine disease. Molecular Genetics & Genomic Medicine. 2(5):383-92. https://doi.org/10.1002/mgg3.88

Bie AS , Bross P. 2014. Substrates of the mitochondrial chaperonin Hsp60. Poster session presented at Euromit 2014, Tampere, Finland.

Mortensen MB , Kjolby M , Gunnersen S , Larsen JV , Palmfeldt J , Falk E , Nykjaer A , Bentzon JF. 2014. Targeting sortilin in immune cells reduces proinflammatory cytokines and atherosclerosis. Journal of Clinical Investigation. 124(12):5317-5322. https://doi.org/10.1172/JCI76002

Bie AS , Bross P , Corydon TJ. 2014. THE HSP60 SUBSTRATE SPECTRUM. Poster session presented at Aarhus University Graduate School of Health, PhD Day 2014, Aarhus, Denmark.

Al-Saaidi RA , Rasmussen TB , Palmfeldt J , Hansen J , Bross P. 2014. THE MISSENSE MUTATION P.ARG471HIS CAUSES DILATED CARDIOMYOPATHY THROUGH A DOMINANT NEGATIVE EFFECT. Poster session presented at Aarhus University Graduate School of Health, PhD Day 2014, Aarhus, Denmark.

Christensen JH , Kvistgaard H , Knudsen JH, Shaikh G, Tolmie J, Cooke S, Pedersen S , Corydon TJ , Gregersen N , Rittig S. 2013. A novel deletion partly removing the AVP gene causes autosomal recessive inheritance of early onset neurohypophyseal diabetes insipidus. Clinical Genetics. 83(1):44-52. https://doi.org/10.1111/j.1399-0004.2011.01833.x

Birkegaard C , Christensen JH, Falorni A, Marzotti S, Minarelli V, Gregersen N , Rittig S. 2013. A novel variation in the AVP gene resulting in familial neurohypophyseal diabetes insipidus in a large Italian kindred. Pituitary. 16(2):152-157. https://doi.org/10.1007/s11102-012-0392-x

Sibbersen C , Palmfeldt J , Hansen J , Gregersen N , Jørgensen KA , Johannsen M. 2013. Development of a chemical probe for identifying protein targets of α-oxoaldehydes. Chemical Communications. 49(38):4012-4. https://doi.org/10.1039/c3cc41099d

Madsen MG , Nørregaard R , Palmfeldt J , Olsen LH , Frøkiær J , Jørgensen TM. 2013. Epidermal growth factor and monocyte chemotactic peptide-1: Potential biomarkers of urinary tract obstruction in children with hydronephrosis. Journal of Pediatric Urology. 9(6 (Part A)):838–845. https://doi.org/10.1016/j.jpurol.2012.11.011

Tonin AM , Fernandez Guerra P , Cornelius N , Olsen R, Wajner M, Gregersen N. 2013. Evidence that fibroblasts from patients affected by medium-chain acyl-CoA dehydrogenase deficiency (MCADD) are under chronic ocidative stress. Poster session presented at 12th International congress of inborn errors of metabolism, Barcelona, Spain.

Fernandez Guerra P , Palmfeldt J, Merinero B, Bross P, Rodriguez-Pombo P. 2013. Fibroblasts from Maple Syrup Urine Disease (MSUD) classic patients showed mitochondrial oxidative stress and protein damage. Poster session presented at 12th International congress of inborn errors of metabolism, Barcelona, Spain.

Wang Y, Goetzman E, Palmfeldt J , Gregersen N, Vockley J. 2013. Functional and physical mapping of the architecture of mitochondrial energy metabolism. Poster session presented at 12th International congress of inborn errors of metabolism, Barcelona, Spain.

Olsen RKJ , Cornelius N , Gregersen N. 2013. Genetic and cellular modifiers of oxidative stress: What can we learn from fatty acid oxidation defects?. Molecular Genetics and Metabolism. 2010(supplement):s31-s39. https://doi.org/10.1016/j.ymgme.2013.10.007

Rohde MC , Corydon TJ , Hansen J , Pedersen CB , Schmidt SP , Gregersen N , Banner J. 2013. Heat stress and sudden infant death syndrome-Stress gene expression after exposure to moderate heat stress. Forensic Science International. 232(1-3):16-24. https://doi.org/10.1016/j.forsciint.2013.06.003

Olsen R , Cornelius N , Corydon TJ , Gregersen N. 2013. Is there a molecular rationale for treating patients with riboflavinresponsive multiple acyl-CoA dehydrogenation deficiency (RR;: MADD) with CoQ10 in addition to riboflavin. Poster session presented at 12th International congress of inborn errors of metabolism, Barcelona, Spain.

Britze AF , Palmfeldt J , Birkler RID , Gregersen N , Ovesen T. 2013. Large-scale proteom-analyse af Cholesteatom "Nye brikker i puslespillet". Abstract from Årsmøde i Dansk Selskab for Otorhinolaryngologi og Hoved-Halskirurgi, Nyborg, Denmark.

Britze AF , Palmfeldt J , Birkler RID , Gregersen N , Ovesen T. 2013. Large-scale proteomic analysis of cholesteatoma. Abstract from 20th IFOS World Congress, Seoul, Korea, Republic of.

Britze AF , Palmfeldt J , Birkler RID , Gregersen N , Ovesen T. 2013. Large-scale proteomic analysis of cholesteatoma. Abstract from Årsmøde i Dansk Selskab for Otorhinolaryngologi og Hoved-Halskirurgi, Nyborg, Denmark.

Magnoni R , Palmfeldt J , Christensen JH , Sand M, Maltecca F, Corydon TJ , West M, Casari G, Bross P. 2013. Late onset motoneuron disorder caused by mitochondrial Hsp60 chaperone deficiency in mice. Neurobiology of Disease. 54C:12-23. https://doi.org/10.1016/j.nbd.2013.02.012

Kleinridders A, Lauritzen HPMM, Ussar S, Christensen JH, Mori MA, Bross P, Kahn CR. 2013. Leptin regulation of Hsp60 impacts hypothalamic insulin signaling. Journal of Clinical Investigation. 123(11):4667-80. https://doi.org/10.1172/JCI67615

Mosegaard S, Olpin SE, Sharrard MJ, Manning NJ, Boneh A, Ryan K, Andreasen C , Kjeldsen M , Gregersen N , Olsen R. 2013. Locus heterogeneity in riboflavin-responsive multiple acyl-CoA dehydrogenation deficiency. Poster session presented at 12th International congress of inborn errors of metabolism, Barcelona, Spain.

Palmfeldt J , Gregersen N , Bross P. 2013. Mass spectrometry analysis of mutant proteins to study mechanisms of inherited disorders. Poster session presented at 12th International congress of inborn errors of metabolism, Barcelona, Spain.

Cornelius N 2013. Molecular rational for riboflavin and CoQ10: treatment in multiple acyl-CoA dehydrogenation deficiency . 58 p.

Rasmussen TB , Palmfeldt J , Nissen PH, Magnoni R, Dalager S , Jensen UB , Kim WY , Heickendorff L , Mølgaard H , Jensen HK, et al. 2013. Mutated Desmoglein-2 Proteins are Incorporated into Desmosomes and Exhibit Dominant-Negative Effects in Arrhythmogenic Right Ventricular Cardiomyopathy. Human Mutation. https://doi.org/10.1002/humu.22289

Povlsen JA , Løfgren B , Dalgas C , Birkler RID , Johannsen M , Støttrup NB , Bøtker HE. 2013. Protection against Myocardial Ischemia-Reperfusion Injury at Onset of Type 2 Diabetes in Zucker Diabetic Fatty Rats Is Associated with Altered Glucose Oxidation. P L o S One. 8(5):e64093. https://doi.org/10.1371/journal.pone.0064093

Rasmussen TB , Hansen J , Nissen PH , Palmfeldt J , Dalager S , Jensen UB , Kim WY , Heickendorff L , Mølgaard H , Jensen HK, et al. 2013. Protein expression studies of desmoplakin mutations in cardiomyopathy patients reveal different molecular disease mechanisms. Clinical Genetics. 84(1):20-30. https://doi.org/10.1111/cge.12056

Edhager AV , Gregersen N , Palmfeldt J. 2013. Proteomic investigation of cultivated fibroblasts from patients with mitochondrial short-chain acyl-CoA dehydrogenase deficiency (SCADD). Poster session presented at 12th International congress of inborn errors of metabolism, Barcelona, Spain.

Schmidt MR , Støttrup NB, Contractor H, Hyldebrandt JA , Johannsen M , Pedersen CM , Birkler R, Ashrafian H, Sørensen KE, Kharbanda RK, et al. 2013. Remote ischemic preconditioning with - but not without - metabolic support protects the neonatal porcine heart against ischemia-reperfusion injury. International Journal of Cardiology. https://doi.org/10.1016/j.ijcard.2013.11.020

Displaying results 151 to 200 out of 421

4

Revised 26.06.2024

-

Helle Just