Find

Department of Clinical Medicine

Research Unit for Molecular Medicine (MMF)

Publications

Sort by: Date | Author | Title

Henriques BJ, Fisher MT, Bross P, Gomes CM. 2011. A polymorphic position in electron transfer flavoprotein modulates kinetic stability as evidenced by thermal stress. FEBS Letters. 585(3):505-10. https://doi.org/10.1016/j.febslet.2011.01.002

Straadt IK, Aaslyng MD, Bertram HCS. 2011. Assesment of meat quality by NMR - An investigation of pork products originating from different breeds. Magnetic Resonance in Chemistry. 49(Suppl. S1):71-78. https://doi.org/10.1002/mrc.2805

Rocha H, Lopes L, Vilarinho L, Ferreira R, Carvalho J, Vitorino R, Santa C, Amado F, Gregersen N. 2011. Characterization of mitochondrial proteome in a severe case of ETF-QO deficiency. Journal of Proteomics. 75(1):221-228. https://doi.org/10.1016/j.jprot.2011.04.025

Lucas TG, Henriques BJ, Rodrigues JV, Bross P , Gregersen N, Gomes CM. 2011. Cofactors and metabolites as potential stabilizers of mitochondrial acyl-CoA dehydrogenases. BBA General Subjects. 1812(12):1658-63. https://doi.org/10.1016/j.bbadis.2011.09.009

Bisgaard C , Christensen T , Henningsen K , Palmfeldt J , Enghild JJ , Wiborg O. 2011. Comparative proteomics in the chronic mild stress model of depression - a search for biomarkers of depression in hippocampal subregions. Poster session presented at Annual society for neuroscience meeting 2011, Washington DC, United States.

Bisgaard C , Christensen T , Henningsen K , Palmfeldt J , Enghild JJ , Wiborg O. 2011. Comparative proteomics in the chronic mild stress model of depression - a search for biomarkers of depression in hippocampal subregions. Poster session presented at 21st Neuropharmacology Conference (Anxiety and Depression), Virginia, United States.

Kvistgaard H 2011. Familial neurohypophyseal diabetes insipidus: The genetic background and molecular pathogenesis. 139 p.

Munksgaard PP, Mansilla F, Brems Eskildsen A-S, Fristrup N , Birkenkamp-Demtröder K , Ulhøi BP , Borre M , Agerbæk M, Hermann GG, Orntoft TF, et al. 2011. Low ANXA10 expression is associated with disease aggressiveness in bladder cancer. B J C. 105(9):1379-87. https://doi.org/10.1038/bjc.2011.404

Ho G, Yonezawa A, Masuda S, Inui K, Sim KG, Carpenter K, Olsen RK, Mitchell JJ, Rhead WJ, Peters G, et al. 2011. Maternal riboflavin deficiency,resulting in transient neonatal-onset glutaric aciduria Type 2, is caused by amicrodeletion in the riboflavin transporter gene GPR172B. Human Mutation. 32/1.

Straadt IK , Young JF, Petersen BO, Duus JØ, Gregersen N , Bross P , Oksbjerg N , Bertram HCS. 2011. Metabolic responses to heat, Anoxia, or oxidative stress elucidated in muscle cell cultures using 13C NMR spectroscopy. Renou JP, Belton PS, Webb GA, editors. In Magnetic Resonance in Food Science: An exciting future. pp. 118-123.

Larsen JKR , Smerup MH , Nørregaard R , Christensen JH, Sivesgaard K, Christensen SD, Christensen K, Sloth E , Torp P , Gregersen N, et al. 2011. Multiplex Analysis of Cardiac Hypertrophic Signaling: Reduced in vivoPhosphorylation of Glycogen Synthase Kinase-3β and Proline-Rich Akt Substrate (PRAS40). Current Signal Transduction Therapy. 6(1):65-70.

Larsen J , Pettersson OJ , Jakobsen M , Thomsen R , Pedersen CB , Hertz JM , Gregersen N , Corydon TJ , Jensen TG. 2011. Myoblasts generated by lentiviral mediated MyoD transduction of myotonic dystrophy type 1 (DM1) fibroblasts can be used for assays of therapeutic molecules. BMC Research Notes. 4:490. https://doi.org/10.1186/1756-0500-4-490

Straadt IK, Aaslyng MD, Bertram HCS. 2011. New gourmet pork products by application of the Iberian and Mangalitza breeds. Side 1-4. Paper presented at 57th ICoMST 2011 - International Congress of Meat Science and Technology: Global challenges to production, processing and consumption of meat , Ghent, Belgium.

Louise B, Meldgaard Lund A, Wibrandt F, Christensen E, Søndergaard C, Gahrn B, Michael Hougaard D, Andresen BS , Gregersen N , Olsen R. 2011. Normal level of plasma free carnitine and acylcarnitine in follow-up samples from a presymptomatic case of carnitine palmitoyl transferase 1 deficiency detected through newborn screening in Denmark. JIMD Reports .

Straadt IK, Aaslyng MD, Bertram HCS. 2011. Novel gourmet pork products by introduction of new breeds. Abstract from LMC Congress FoodInFront, Odense, Denmark.

Gregersen N , Bross P , Olsen R , Palmfeldt J , Corydon TJ. 2011. Protein interaction and genetic disease. In Encyclopedia of Life Sciences.

Bross P , Andresen BS , Corydon TJ , Gregersen N. 2011. Protein Misfolding and degradation in Genetic Diseases (updated version). Encyclopedia of the Human Genome. Nature Publishing Group.

Palmfeldt J , Vang S , Stenbroen V, Pavlou E, Baycheva M, Buchal G, Monavari AA, Augoustides-Savvopoulou P, Mandel H, Gregersen N. 2011. Proteomics Reveals that Redox Regulation Is Disrupted in Patients with Ethylmalonic Encephalopathy. Journal of Proteome Research. https://doi.org/10.1021/pr101218d

Hansen J , Palmfeldt J , Vang S , Corydon TJ , Gregersen N , Bross P. 2011. Quantitative proteomics reveals cellular targets of celastrol. P L o S One. 6(10).

Hansen J , Palmfeldt J , Vang S , Corydon TJ , Gregersen N , Bross P. 2011. Quantitative proteomics reveals cellular targets of celastrol. P L o S One. 6(10):e26634. https://doi.org/10.1371/journal.pone.0026634

Koed Doktor T, Schroeder LD , Vested A , Palmfeldt J, Andersen HS, Gregersen N, Andresen BS. 2011. SMN2 exon 7 splicing is inhibited by binding of hnRNP A1 to a common ESS motif that spans the 3' splice site. Human Mutation. 32(2):220-30. https://doi.org/10.1002/humu.21419

Schmidt SP , Corydon TJ , Pedersen CB , Vang S , Palmfeldt J , Stenbroen V, Wanders RJA, Ruiter JPN, Gregersen N. 2011. Toxic response caused by a misfolding variant of the mitochondrial protein short-chain acyl-CoA dehydrogenase. Journal of Inherited Metabolic Disease. 34. https://doi.org/10.1007/s10545-010-9255-7

Sykut-Cegielska J, Gradowska W, Piekutowska-Abramczuk D, Andresen BS , Olsen RKJ, Ołtarzewski M, Pronicki M, Pajdowska M, Bogdańska A, Jabłońska E, et al. 2011. Urgent metabolic service improves survival in long-chain 3-hydroxyacyl-CoA dehydrogenase (LCHAD) deficiency detected by symptomatic identification and pilot newborn screening. Journal of Inherited Metabolic Disease. 34(1):185-95. https://doi.org/10.1007/s10545-010-9244-x

Zolkipli Z, Pedersen CB, Lamhonwah A-M, Gregersen N, Tein I. 2011. Vulnerability to Oxidative Stress In Vitro in Pathophysiology of Mitochondrial Short-Chain Acyl-CoA Dehydrogenase Deficiency: Response to Antioxidants. P L o S One. 6(4):e17534. https://doi.org/10.1371/journal.pone.0017534

Hansen J , Bross P. 2010. A cellular viability assay to monitor drug toxicity. Methods in molecular biology (Clifton, N.J.). 648:303-11. https://doi.org/10.1007/978-1-60761-756-3_21

Piekutowska-Abramczuk D, Olsen RKJ, Wierzba J, Popowska E, Jurkiewicz D, Ciara E, Ołtarzewski M, Gradowska W, Sykut-Cegielska J, Krajewska-Walasek M, et al. 2010. A comprehensive HADHA c.1528G>C frequency study reveals high prevalence of long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency in Poland. Journal of Inherited Metabolic Disease. https://doi.org/10.1007/s10545-010-9190-7

Piekutowska-Abramczuk D, Olsen R, Wierzba J, Popowska E, Jurkiewicz D, Ciara E, Ołtarzewski M, Gradowska W, Sykut-Cegielska J, Krajewska-Walasek M, et al. 2010. A comprehensive HADHA c.1528G>C frequency studyreveals high prevalence of long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency in Poland. Journal of Inherited Metabolic Disease.

Dessein A-F, Fontaine M, Andresen BS , Gregersen N, Brivet M, Rabier D, Napuri-Gouel S, Dobbelaere D, Mention-Mulliez K, Martin-Ponthieu A, et al. 2010. A novel mutation of the ACADM gene (c.145C>G) associated with the common c.985A>G mutation on the other ACADM allele causes mild MCAD deficiency: a case report. Orphanet Journal of Rare Diseases. 5:26. https://doi.org/10.1186/1750-1172-5-26

Singh R , Kølvraa S , Bross PG, Christensen K, Bathum L, Gregersen N, Tan Q, Rattan S. 2010. Anti-inflammatory heat shock protein 70 genes are positively associated with human survival. Current Pharmaceutical Design. 16(7):796-801.

Pedersen CB, Zolkipli Z, Vang S , Palmfeldt J , Kjeldsen M , Stenbroen V , Schmidt S, Wanders RJA, Ruiter JPN, Wibrand F, et al. 2010. Antioxidant dysfunction: potential risk for neurotoxicity in ethylmalonic aciduria. Journal of Inherited Metabolic Disease. 33(3):211-22. https://doi.org/10.1007/s10545-010-9086-6

Birkler RID , Støttrup N, Hermannson S, Nielsen TT , Gregersen N , Bøtker HE , Andreasen MF , Johannsen M. 2010. A UPLC-MS/MS application for profiling of intermediary energy metabolites in microdialysis samples--a method for high-throughput. Journal of Pharmaceutical and Biomedical Analysis. 53(4):983-90. https://doi.org/10.1016/j.jpba.2010.06.005

Palmfeldt J , Stenbroen V , Vang S , Gregersen N. 2010. CHARACTERIZATION OF THE MITOCHONDRIAL PROTEOME IN CULTIVATED CELLS FROM PATIENTS SUFFERING FROM ETHYLMALONIC ENCEPHALOPATHY. Molecular Genetics and Metabolism. (1).

Gregersen N , Olsen RKJ. 2010. Disease mechanisms and protein structures in fatty acid oxidation defects. Journal of Inherited Metabolic Disease. https://doi.org/10.1007/s10545-010-9046-1

Henriques BJ, Olsen RK , Bross P, Gomes CM. 2010. Emerging roles for riboflavin in functional rescue of mitochondrial β-oxidation flavoenzymes. Current Medicinal Chemistry. 17(32):3842-54.

Olsen R, Dobrowolski SF, Kjeldsen M, Hougaard D, Simonsen H, Gregersen N, Andresen BS. 2010. High-resolution melting analysis, a simple and effective method for reliable mutation scanning and frequency studies in the ACADVL gene. Journal of Inherited Metabolic Disease. 33:247-60.

Olsen RKJ, Dobrowolski SF, Kjeldsen M, Hougaard D, Simonsen H, Gregersen N , Andresen BS. 2010. High-resolution melting analysis, a simple and effective method for reliable mutation scanning and frequency studies in the ACADVL gene. Journal of Inherited Metabolic Disease. 33(3):247-60. https://doi.org/10.1007/s10545-010-9101-y

Madsen PP 2010. Identification and characterization of prognostic and predictive markers in bladder cancer. Aarhus Universitet.

Christensen JH , Nielsen MN , Hansen J , Füchtbauer A , Füchtbauer E-M , West M , Corydon TJ , Gregersen N , Bross P. 2010. Inactivation of the hereditary spastic paraplegia-associated Hspd1 gene encoding the Hsp60 chaperone results in early embryonic lethality in mice. Cell Stress & Chaperones. 15(6):851-863. https://doi.org/10.1007/s12192-010-0194-x

Schmidt S 2010. Investigation of a Misfolded Mitochondrial Protein - The cellular handling of a disease-accociated variant of short-chain acyl-CoA dehydrogenase (SCAD). Aarhus Universitet.

Baiges I, Palmfeldt J, Blade C, Gregersen N, Arola L. 2010. Lipogenesis is decreased by grape seed proanthocyanidins according to liver proteomics of rats fed a high fat diet. Molecular and Cellular Proteomics. https://doi.org/10.1074/mcp.M000055-MCP201

Bross P , Palmfeldt J , Hansen J , Vang S , Gregersen N. 2010. Measuring Consequences of Protein Misfolding and Cellular Stress Using OMICS Techniques. Methods in Molecular Biology. 648:119-35. https://doi.org/10.1007/978-1-60761-756-3_8

Straadt IK , Young JF, Petersen BO, Duus JØ, Gregersen N , Bross P , Oksbjerg N , Bertram HC. 2010. Metabolic profiling of heat or anoxic stress in mouse C2C12 myotubes using multinuclear magnetic resonance spectroscopy. Metabolism. 59(6):814-823. https://doi.org/10.1016/j.metabol.2009.09.029

Schmidt S , Corydon TJ , Pedersen CB , Bross P , Gregersen N. 2010. Misfolding of short-chain acyl-CoA dehydrogenase leads to mitochondrial fission and oxidative stress. Molecular Genetics and Metabolism. 100(2):155-162.

Henriques BJ, Bross P, Gomes CM. 2010. Mutational hotspots in electron transfer flavoprotein underlie defective folding and function in multiple acyl-CoA dehydrogenase deficiency. BBA General Subjects. https://doi.org/10.1016/j.bbadis.2010.07.015

Straadt IK , Young JF , Bross P , Gregersen N , Oksbjerg N , Theil PK , Bertram HC. 2010. NMR-Based Metabonomic Investigation of Heat Stress in Myotubes Reveals a Time-Dependent Change in the Metabolites. Journal of Agricultural and Food Chemistry. 58:6376-6386. https://doi.org/10.1021/jf904197u

Straadt IK , Young JF, Petersen BO, Duus JØ, Gregersen N , Bross P , Oksbjerg N , Theil PK , Bertram HC. 2010. Oxidative stress-induced metabolic changes in mouse C2C12 myotubes studied with high-resolution 13C, 1H, and 31P NMR spectroscopy. Journal of Agricultural and Food Chemistry. 58(3):1918-26. https://doi.org/10.1021/jf903505a

Hansen J , Lesnikova I , Lundemose JB. 2010. PCR-based quality evaluation of DNA extracted from autopsy tissue material archived at department of Forensic Medicine Aarhus University. Poster session presented at Årsmøde i Dansk Selskab for Retsmedicin, Odense, Denmark.

Hansen J , Lesnikova I , Lundemose JB. 2010. PCR-based quality evaluation of DNA extracted from autopsy tissue material archived at department of Forensic Medicine Aarhus University. Abstract from Årsmøde i Dansk Selskab for Retsmedicin, Odense, Denmark.

Gregersen N , Bross P. 2010. Protein misfolding and cellular stress: an overview. Methods in Molecular Biology. 648:3-23. https://doi.org/10.1007/978-1-60761-756-3_1

Pedersen CB , Gregersen N. 2010. Stress response profiles in human fibroblasts exposed to heat shock or oxidative stress. Methods in Molecular Biology. 648.

Displaying results 251 to 300 out of 438

6

Revised 10.01.2025

-

Helle Just