Determinants of Prognosis in Pancreatic Cancer Patients

Aim

To better understand determinants of survival after pancreatic cancer (PC) surgery to improve outcomes.

Study design

A series of cohort studies.

About the project

PC is a highly fatal disease with a 5-year survival of 10%. Surgery is the only chance for long-term survival, and patients undergoing surgical treatment have a 5-year survival of ~25%. However, PC surgery is a major procedure with a substantial risk of postoperative complications (30-50%) and death (2-3%). Around ~20% of patients undergoing curative-intent surgery experiences recurrence within 6 months. In these patients, the surgical procedure can be considered futile, and it is therefore important to thoroughly outweigh risks and benefits prior to surgical treatment. As clinicians, we need improved knowledge on patient-specific expected outcomes after PC surgery.

Publications:

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Research area:

HPB surgery
 

Project Investigator (PI)

Project participants:

  • Jakob Kirkegård, MD, PhD, Associate Professor, Department of Surgery, Aarhus University Hospital
  • Frank Viborg Mortensen, MD, DMSc, Consultant Surgeon, Department of Surgery, Aarhus University Hospital
  • Anders Riegels Knudsen, MD, DMSc, Consultant Surgeon, Department of Surgery, Aarhus University Hospital
  • Uffe Heide-Jørgensen, cand.scient, PhD, Department of Clinical Epidemiology, Aarhus University Hospital

Funding:

  • Danish Cancer Society