Nicole Antolini

Title

PhD Student, MD, PhD

Primary affiliation

Nicole Antolini

Areas of expertise

  • Copper metabolism
  • PET imaging
  • Wilson’s disease
  • Rare genetic liver disorders
  • Brain copper in Wilson's Disease

Contact information

Email address

Profile

Medical doctor and researcher specializing in copper metabolism with a focus on Wilson's disease - a rare genetic disorder affecting the liver and the brain. My research explores the pharmacokinetics of copper binding compounds, particularly their effects on brain copper accumulation in the neurological form of Wilson's disease. Using Pet imaging, investigate cerebral and hepatic copper dynamics and evaluate therapeutic potential of novel compounds in animal models.

Job responsibilities

Design and Conduct Experiments: Plan, execute, and oversee nuclear medicine experiments, ensuring adherence to established protocols and safety guidelines.
Protocol Development: Draft and refine research protocols, incorporating feedback from interdisciplinary teams to optimize study designs.
Radiotracer Handling: Manage and administer radioactive tracers, such as ⁶⁴Cu, following strict safety and regulatory standards.
Data Analysis: Process and analyze imaging data using specialized software to interpret tracer distribution and kinetics.
Literature Review: Conduct comprehensive reviews of current scientific literature to inform experimental approaches and contextualize findings.
Manuscript Preparation: Author scientific papers detailing research findings, including drafting abstracts, methodologies, results, and discussions.
Participate in weekly research meetings and university courses to stay abreast of advancements in the field and contribute to academic discourse.