Publications

The structural heart disease group at Aarhus University and Aarhus University Hospital has a high level of clinical research activity. Here you can see our recent published papers. 

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List of publications

Yuriditsky, E., Lyhne, M. D., Horowitz, J. M. & Dudzinski, D. M. (2026). Critical Care Management of Acute Pulmonary Embolism. Journal of Intensive Care Medicine, 41(3), 8850666241311512. https://doi.org/10.1177/08850666241311512
Lee, E. S., Baltsen, C. D., Stubblefield, W. B., Granfeldt, A., Andersen, A., Stannek, K., Dudzinski, D. M., Kabrhel, C. & Lyhne, M. D. (2026). Intubation and Mechanical Ventilation in Patients with Acute Pulmonary Embolism: A Scoping Review. Journal of Intensive Care Medicine, 41(1), 3-11. https://doi.org/10.1177/08850666241285862
Lakkireddy, D., Ellis, C. R., Thaler, D., Swarup, V., Gambhir, A., Hermiller, J., Nielsen-Kudsk, J. E., Worthley, S., Nair, D., Schmidt, B., Horton, R., Gupta, N., Anderson, J. A., Zhao, H., Alkhouli, M. & Windecker, S. (2025). 5-Year Results From the AMPLATZER Amulet Left Atrial Appendage Occluder Randomized Controlled Trial. Journal of the American College of Cardiology, 85(11), 1141-1153. https://doi.org/10.1016/j.jacc.2024.10.101
Potpara, T., Markovic, B., Grygier, M., Genovesi, S., Tzikas, A., Boveda, S., Nielsen-Kudsk, J. E., Boriani, G., Lip, G. Y. H. & Camm, A. J. (2025). Adherence to oral thromboprophylaxis in atrial fibrillation: An overview for clinicians. EP Europace, 27(11), Article euaf250. https://doi.org/10.1093/europace/euaf250
Nielsen-Kudsk, J. E., Aminian, A., De Backer, O., Iriart, X., Berti, S., Galea, R., Freixa, X., Räber, L., Cruz-Gonzalez, I., Wunderlich, N. C. & Garot, P. (2025). A new implanter classification system for left atrial appendage closure from the European Left Atrial Appendage Closure Club (ELAACC). EuroIntervention, 21(11), e594-e604. https://doi.org/10.4244/EIJ-D-24-00954
Potpara, T., Grygier, M., Haeusler, K. G., Nielsen-Kudsk, J. E., Berti, S., Genovesi, S., Marijon, E., Boveda, S., Tzikas, A., Boriani, G., Boersma, L. V. A., Tondo, C., Potter, T. D., Lip, G. Y. H., Schnabel, R. B., Bauersachs, R., Senzolo, M., Basile, C., Bianchi, S. ... Camm, A. J. (2025). An International Consensus Practical Guide on Left Atrial Appendage Closure for the Non-implanting Physician: Executive Summary. Thrombosis and Haemostasis, 125(9), 825-846. https://doi.org/10.1055/a-2469-4896
Samaras, A., Karakasis, P., Feidakis, A., Giannakoulas, G., Fragakis, N., Nielsen-Kudsk, J.-E., Freixa, X., Nair, D. G., Freeman, J. V., Bergmann, M., Landmesser, U. & Tzikas, A. (2025). Antithrombotic strategies and DOAC dosing following left atrial appendage occlusion: a network meta-analysis. European heart journal - Cardiovascular pharmacotherapy. Advance online publication. https://doi.org/10.1093/ehjcvp/pvaf078
Nielsen-Kudsk, J. E., Schmidt, B., Windecker, S., Shah, N., Gray, W., Ellis, C. R., Koulogiannis, K., Anderson, J. A., Gage, R. & Lakkireddy, D. (2025). Characterization and Clinical Outcomes of High-Risk Device-Related Thrombus in the Amulet IDE Trial. JACC: Clinical Electrophysiology, 11(7), 1543-1554. https://doi.org/10.1016/j.jacep.2025.02.016
Bshennaty, A., Vogl, B. J., Saleh, G., Bavo, A. M., Sularz, A., Ghazal-Aswad, K., Kramer, A. D., Jia, Y., De Beule, M., Nielsen-Kudsk, J. E., De Backer, O., Alkhouli, M. & Hatoum, H. (2025). Comparison of Flow Dynamics After Left Atrial Appendage Occlusion With the Watchman FLX Versus Amulet Devices: Implications for Device-Related Thrombosis. Catheterization and Cardiovascular Interventions, 106(4), 2084-2092. https://doi.org/10.1002/ccd.31710
Garot, P., Nielsen-Kudsk, J.-E., Freixa, X., Berti, S., Wunderlich, N., Cruz-Gonzalez, I., Räber, L., Aminian, A. & De Backer, O. (2025). Contemporary European practice in left atrial appendage closure: results from a survey focusing on planning, techniques and post-implantation management. BMJ Open, 15(2), e090541. Article e090541. https://doi.org/10.1136/bmjopen-2024-090541
Garot, P., Cepas-Guillén, P., Flores-Umanzor, E., Leduc, N., Bajoras, V., Perrin, N., McInerney, A., Lafond, A., Farjat-Pasos, J., Millán, X., Zendjebil, S., Ibrahim, R., Salinas, P., de Backer, O., Cruz-González, I., Arzamendi, D., Sanchis, L., Nombela-Franco, L., O'Hara, G. ... Freixa, X. (2025). Impact of intensive versus nonintensive antithrombotic treatment on device-related thrombus after left atrial appendage closure. Revista Espanola de Cardiologia, 78(8), 668-678. https://doi.org/10.1016/j.recesp.2024.11.015
Sonne-Holm, E., Bang, L. E., Carlsen, J., Andersen, A., Hougaard, M., Christensen, M. K., Holmvang, L., Sørensen, R., Ersbøll, M. & Kjærgaard, J. (2025). Kateterbaseret behandling til patienter med akut lungeemboli. Ugeskrift for Læger, 187(51), Article V07250571. https://doi.org/10.61409/V07250571
OPTION Trial Investigators (2025). Left Atrial Appendage Closure after Ablation for Atrial Fibrillation. The New England Journal of Medicine, 392(13), 1277-1287. https://doi.org/10.1056/NEJMoa2408308
Galea, R., Bini, T., Korsholm, K., Sedaghat, A., Aminian, A., Vij, V., Perich Krsnik, J., Chalkou, K., Siontis, G., Roten, L., Nielsen-Kudsk, J. E. & Räber, L. (2025). Left Atrial Appendage Closure in Patients Refusing Oral Anticoagulation: The LAAC-REFUSAL Study. Journal of the American Heart Association, 14(19), 1-10. Article e040404. https://doi.org/10.1161/JAHA.124.040404
Kefer, J., De Backer, O., Aminian, A., Freixa, X., Berti, S., Cruz-Gonzalez, I., Räber, L., Wunderlich, N., Garot, P., Nielsen-Kudsk, J. E. & On Behalf Of The European Left Atrial Appendage Closure Club Elaacc (2025). Management of device embolisation during left atrial appendage closure. EuroIntervention, 21(15), e838-e846. https://doi.org/10.4244/EIJ-D-24-00812
Shah, A. P., Freeman, J. V., Alkhouli, M., Agarwal, H., Coylewright, M., Makkar, A., Anderson, J., Gage, R., Freixa, X., Nielsen-Kudsk, J. E. & Lakkireddy, D. (2025). Outcomes for single antiplatelet, dual antiplatelet, or oral anticoagulation after Amulet: Insights from EMERGE LAA post-approval study. Cardiovascular revascularization medicine : including molecular interventions. Advance online publication. https://doi.org/10.1016/j.carrev.2025.07.012
Meulengracht, D. E., Petersen, J. K., Veien, K. T., de Backer, O., Østergaard, L., Ihlemann, N., Poulsen, S. H., Dahl, J. S., Freeman, P., Andersen, A., Møller, J. E., Køber, L. & Fosbøl, E. (2025). Outcomes in patients undergoing transcatheter edge-to-edge mitral valve repair as compared to a general and heart failure population. International Journal of Cardiology, 439, Article 133605. https://doi.org/10.1016/j.ijcard.2025.133605
Jacquemyn, X., Sá, M. P., Korsholm, K., Nielsen-Kudsk, J. E., Iriart, X., Saw, J., Alkhouli, M., Jain, S., Bittencourt, M. S. & Sultan, I. (2025). Outcomes of Left Atrial Appendage Patency After Device Closure Detected by Cardiac CT: A Meta-Analysis. JACC: Cardiovascular Imaging, 18(12), 1348-1359. https://doi.org/10.1016/j.jcmg.2025.07.018
Lyhne, J. D., Hansen, V. B., Vestergaard, L. D., Hosbond, S. E., Busk, M., Gnanaganesh, M., Maae, E., Havelund, B. M., Hansen, T. F., Timm, S., Jensen, L. H. & Lyhne, M. D. (2025). Primary prevention of cardiotoxicity in cancer patients treated with fluoropyrimidines: a randomized controlled trial. Cardio-Oncology, 11(1), Article 48. https://doi.org/10.1186/s40959-025-00344-3
Slobod, D., Zochios, V., Yusuff, H., Lyhne, M. D. & Denault, A. Y. (2025). Right Ventricular Hemodynamics in the Acute Respiratory Distress Syndrome: Monitoring and Implications for Clinical Management. American Journal of Respiratory and Critical Care Medicine. Advance online publication. https://doi.org/10.1164/rccm.202505-1125CI
Smeele, P., Braams, N. J., Vermunt, L., Kianzad, A., Rodenburg, T. C., Stilling, E., Andersen, S., Andersen, M. J., Mellemkjær, S., Nossent, E. J., Aman, J., Beijk, M. A. M., Lely, R. J., Winkelman, J. A., Oosterveer, F., Marcus, T., Vonk Noordegraaf, A., Meijboom, L. J., Teunissen, C. E. ... Bogaard, H. J. (2025). Similar quality of life after balloon pulmonary angioplasty or pulmonary endarterectomy for CTEPH. JHLT Open, 8, Article 100223. https://doi.org/10.1016/j.jhlto.2025.100223
Falster, C., Egholm, G., Lambrechtsen, J., Andersen, A., Gaist, T. A., Bauersach, R., Klok, F. A. & Vonk-Noordegraaf, A. (2025). Treatment of acute pulmonary embolism: A comparison of international guideline recommendations. Journal of Thrombosis and Haemostasis. Advance online publication. https://doi.org/10.1016/j.jtha.2025.11.021
Eppinger, S., Piayda, K., Galea, R., Sandri, M., Maarse, M., Güner, A., Karabay, C. Y., Pershad, A., Ding, W. Y., Aminian, A., Akin, I., Davtyan, K. V., Chugunov, I. A., Marijon, E., Rosseel, L., Schmidt, T. R., Amabile, N., Korsholm, K., Lund, J. ... Nielsen-Kudsk, J. E. (2024). Embolization of percutaneous left atrial appendage closure devices: timing, management and clinical outcomes. Cardiovascular revascularization medicine : including molecular interventions, 64, 7-14. https://doi.org/10.1016/j.carrev.2024.02.014