Publications

The structural heart disease group at Aarhus University and Aarhus University Hospital has a high level of clinical research activity. Here you can see our recent published papers.

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List of publications

Palm, P., Qvist, I., Rasmussen, T. B., Christensen, S. W., Håkonsen, S. J. & Risom, S. S. (2020). Educational interventions to improve outcomes in patients with atrial fibrillation-a systematic review. International Journal of Clinical Practice, 74(11), Article e13629. https://doi.org/10.1111/ijcp.13629

Lyhne, M. D., Witkin, A. S., Dasegowda, G., Tanayan, C., Kalra, M. K. & Dudzinski, D. M. (2022). Evaluating cardiopulmonary function following acute pulmonary embolism. Expert Review of Cardiovascular Therapy, 20(9), 747-760. https://doi.org/10.1080/14779072.2022.2108789

Korsholm, K., Berti, S., Iriart, X., Saw, J., Wang, D. D., Cochet, H., Chow, D., Clemente, A., De Backer, O., Møller Jensen, J. & Nielsen-Kudsk, J. E. (2020). Expert Recommendations on Cardiac Computed Tomography for Planning Transcatheter Left Atrial Appendage Occlusion. JACC. Cardiovascular interventions, 13(3), 277-292. https://doi.org/10.1016/j.jcin.2019.08.054

Holmes, D. R., Korsholm, K., Rodés-Cabau, J., Saw, J., Berti, S. & Alkhouli, M. A. (2023). Left atrial appendage occlusion. EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 18(13), e1038-e1065. https://doi.org/10.4244/EIJ-D-22-00627

Freixa, X., Aminian, A., Tzikas, A., Saw, J., Nielsen-Kudsk, J.-E., Ghanem, A., Schmidt, B. & Hildick-Smith, D. (2020). Left atrial appendage occlusion with the Amplatzer Amulet: update on device sizing. Journal of Interventional Cardiac Electrophysiology, 59(1), 71-78. https://doi.org/10.1007/s10840-019-00699-5

Alkhouli, M., De Backer, O., Ellis, C. R., Nielsen-Kudsk, J. E., Sievert, H., Natale, A., Lakkireddy, D. & Holmes, D. R. (2023). Peridevice Leak After Left Atrial Appendage Occlusion: Incidence, Mechanisms, Clinical Impact, and Management. JACC. Cardiovascular interventions, 16(6), 627-642. https://doi.org/10.1016/j.jcin.2022.12.006

Pastormerlo, L. E., De Caterina, A. R., Esposito, A., Korsholm, K. & Berti, S. (2024). State-of-the-Art of Transcatheter Left Atrial Appendage Occlusion. Journal of Clinical Medicine, 13(4), Article 939. https://doi.org/10.3390/jcm13040939

Alkhouli, M. & Nielsen-Kudsk, J. E. (2023). The Case for Intracardiac Echo to Guide Left Atrial Appendage Closure. Cardiac Electrophysiology Clinics, 15(2), 151-156. https://doi.org/10.1016/j.ccep.2023.01.010

Lyhne, M. D., Giordano, N., Dudzinski, D., Torrey, J., Wang, G., Zheng, H., Parry, B. A., Kalra, M. K. & Kabrhel, C. (2023). Authors' reply. Emergency Radiology, 30(4), 565-566. https://doi.org/10.1007/s10140-023-02145-6

Andersen, A., Musialek, P., Araszkiewicz, A., Schultz, J., Nielsen-Kudsk, J. E., Tekieli, L., Zajdel, W., Sławek-Szmyt, S., Taff, Y. & Weinberg, I. (2023). First-in-Human Trial of Mechanical-Electric Thrombectomy in Acute Pulmonary Embolism. JACC: Cardiovascular Interventions, 16(5), 623-625. https://doi.org/10.1016/j.jcin.2022.12.021

Sørensen, H., Hedegaard, J. N., Andersen, A., Nielsen-Kudsk, J. E., Johnsen, S. P. & Simonsen, C. Z. (2023). Ischemic Stroke Related to a Patent Foramen Ovale Occurs in the Morning Hours. Stroke, 54(9), e413-e414. https://doi.org/10.1161/STROKEAHA.123.044009

Lakkireddy, D., Thaler, D., Ellis, C. R., Swarup, V., Gambhir, A., Hermiller, J., Nielsen-Kudsk, J. E., Worthley, S., Nair, D., Schmidt, B., Horton, R., Gupta, N., Anderson, J. A., Gage, R., Alkhouli, M. & Windecker, S. (2023). 3-Year Outcomes From the Amplatzer Amulet Left Atrial Appendage Occluder Randomized Controlled Trial (Amulet IDE). JACC. Cardiovascular interventions, 16(15), 1902-1913. https://doi.org/10.1016/j.jcin.2023.06.022

Kristiansen, S. B., Solskov, L., Jessen, N., Løfgren, B., Schmitz, O., Nielsen-Kudsk, J. E., Nielsen, T. T., Bøtker, H. E. & Lund, S. (2009). 5-Aminoimidazole-4-carboxamide-1-beta-d-ribofuranoside Increases Myocardial Glucose Uptake during Reperfusion and Induces Late Pre-conditioning: Potential Role of AMP-Activated Protein Kinase. Basic & Clinical Pharmacology & Toxicology, 105(1), 10-16. https://doi.org/10.1111/j.1742-7843.2009.00402.x

Vildbrad, M. D., Andersen, A., Holmboe, S., Ringgaard, S., Nielsen, J. M. & Nielsen-Kudsk, J. E. (2014). Acute effects of levosimendan in experimental models of right ventricular hypertrophy and failure. Pulmonary Circulation, 4(3), 511-519. https://doi.org/10.1086/677366

Andersen, A., Nielsen, J. M., Rasalingam, S., Sloth, E. & Nielsen-Kudsk, J. E. (2013). Acute effects of sildenafil and dobutamine in the hypertrophic and failing right heart in vivo. Pulmonary Circulation, 3(3), 599-610. https://doi.org/10.1086/674327

Qvist, I., Søgaard, R., Lindholt, J. S., Lorentzen, V., Hallas, J. & Frost, L. (2019). Adherence to prescribed drugs among 65-74 years old men diagnosed with abdominal aortic aneurysm or peripheral arterial disease in a screening trial: A VIVA substudy. European Journal of Vascular and Endovascular Surgery, 57(3), 442-450. https://doi.org/10.1016/j.ejvs.2018.09.023

Maagaard, M., Boutrup, N., Udholm, S., Ahlstrup, M., Nielsen-Kudsk, J. E., Ringgaard, S. & Hjortdal, V. (2023). Adults with small, unrepaired atrial septal defects have reduced cardiac index during exercise. Cardiology in the Young, 33(10), 1981-1991. https://doi.org/10.1017/S1047951122003742

Larsen, S. H., Emmertsen, K., Hjortdal, V. E. & Nielsen-Kudsk, J. E. (2014). Adverse Events in Transcatheter Interventions for Congenital Heart Disease: A Population-based Long-term Study. Congenital Heart Disease, 10(2), 153-158. https://doi.org/10.1111/chd.12218

Schultz, J., Giordano, N., Zheng, H., Parry, B. A., Barnes, G. D., Heresi, G. A., Jaber, W., Wood, T., Todoran, T., Courtney, D. M., Naydenov, S., Khandhar, S., Green, P., Kabrhel, C. & Natl Pert Consortium Res Comm (2019). A multidisciplinary pulmonary embolism response team (PERT)-experience from a national multicenter consortium. Pulmonary Circulation, 9(3), 1-10. https://doi.org/10.1177/2045894018824563

Andersen, C. U., Hilberg, O., Mellemkjær, S., Nielsen-Kudsk, J. E. & Simonsen, U. (2011). Apelin and pulmonary hypertension. Pulmonary Circulation, 1(3), 334-46. https://doi.org/10.4103/2045-8932.87299

Schultz, J., Andersen, A., Gade, I.-L., Ringgaard, S., Kjaergaard, B. & Nielsen-Kudsk, J. E. (2018). A porcine in-vivo model of acute pulmonary embolism: A porcine in-vivo model of acute pulmonary embolism. Pulmonary Circulation, 8(1). https://doi.org/10.1177/2045893217738217

Andersen, S., Schultz, J. G., Holmboe, S., Axelsen, J. B., Hansen, M. S., Lyhne, M. D., Nielsen-Kudsk, J. E. & Andersen, A. (2018). A Pulmonary Trunk Banding Model of Pressure Overload Induced Right Ventricular Hypertrophy and Failure. Journal of Visualized Experiments, 2018(141), Article e58050. https://doi.org/10.3791/58050

Kallonen, J., Korsholm, K., Bredin, F., Corbascio, M., Jønsson Andersen, M., Ilkjær, L. B., Mellemkjær, S. & Sartipy, U. (2022). Association of residual pulmonary hypertension with survival after pulmonary endarterectomy for chronic thromboembolic pulmonary hypertension. Pulmonary Circulation, 12(2), e12093. Article e12093. https://doi.org/10.1002/pul2.12093

Andersen, A., Matzen, K. L., Andersen, G., Settergren, M., Sjostrand, C., Iversen, H. K., Roine, R. O., Hildick-Smith, D., Spence, J. D., Rhodes, J. F., Kasner, S. E., Sondergaard, L. & Nielsen-Kudsk, J. E. (2022). Atrial fibrillation after closure of patent foramen ovale in the REDUCE clinical study. Catheterization and Cardiovascular Interventions, 99(5), 1551-1557. https://doi.org/10.1002/ccd.30019

Nyboe, C., Olsen, M. S., Nielsen-Kudsk, J. E. & Hjortdal, V. E. (2015). Atrial fibrillation and stroke in adult patients with atrial septal defect and the long-term effect of closure. Heart, 101(9), 706-11. https://doi.org/10.1136/heartjnl-2014-306552

Lang, I. M., Andreassen, A. K., Andersen, A., Bouvaist, H., Coghlan, G., Escribano-Subias, P., Jansa, P., Kopec, G., Kurzyna, M., Matsubara, H., Meyer, B. C., Palazzini, M., Post, M. C., Pruszczyk, P., Räber, L., Roik, M., Rosenkranz, S., Wiedenroth, C. B., Redlin-Werle, C. & Brenot, P. (2023). Balloon pulmonary angioplasty for chronic thromboembolic pulmonary hypertension: a clinical consensus statement of the ESC working group on pulmonary circulation and right ventricular function. European Heart Journal, 44(29), 2659-2671. https://doi.org/10.1093/eurheartj/ehad413

Andersen, A., Hansen, J. V., Dragsbaek, S. J., Maeng, M., Andersen, M. J., Andersen, G., Mellemjkaer, S., Ilkjær, L. B. & Nielsen-Kudsk, J. E. (2022). Balloon pulmonary angioplasty for patients with chronic thromboembolic pulmonary hypertension previously operated by pulmonary endarterectomy. Pulmonary Circulation, 12(3), Article e12115. https://doi.org/10.1002/pul2.12115

Andersen, S., Reese-Petersen, A. L., Braams, N., Andersen, M. J., Mellemkjær, S., Andersen, A., Bogaard, H. J., Genovese, F. & Nielsen-Kudsk, J. E. (2023). Biomarkers of collagen turnover and wound healing in chronic thromboembolic pulmonary hypertension patients before and after pulmonary endarterectomy. International Journal of Cardiology, 384, 82-88. https://doi.org/10.1016/j.ijcard.2023.05.016

Smits, J., Tasev, D., Andersen, S., Szulcek, R., Botros, L., Ringgaard, S., Andersen, A., Vonk-Noordegraaf, A., Koolwijk, P. & Bogaard, H. J. (2018). Blood Outgrowth and Proliferation of Endothelial Colony Forming Cells are Related to Markers of Disease Severity in Patients with Pulmonary Arterial Hypertension. International Journal of Molecular Sciences , 19(12), Article 3763. https://doi.org/10.3390/ijms19123763

Kramer, A. D., Korsholm, K., Jensen, J. M., Nørgaard, B. L., Peelukhana, S., Herbst, T., Horton, R., Kar, S., Saw, J., Alkhouli, M. & Nielsen-Kudsk, J. E. (2023). Cardiac computed tomography following Watchman FLX implantation: device-related thrombus or device healing? European Heart Journal Cardiovascular Imaging, 24(2), 250-259. https://doi.org/10.1093/ehjci/jeac222

Bertelsen, J. B., Refsgaard, J., Kanstrup, H., Johnsen, S. P., Qvist, I., Christensen, B. & Christensen, K. L. (2017). Cardiac rehabilitation after acute coronary syndrome comparing adherence and risk factor modification in a community-based shared care model versus hospital-based care in a randomised controlled trial with 12 months of follow-up. European Journal of Cardiovascular Nursing, 16(4), 334-343 . https://doi.org/10.1177/1474515116666781

Kristiansen, S. B., Løfgren, B., Støttrup, N., Kimose, H.-H., Nielsen-Kudsk, J. E., Bøtker, H. E. & Nielsen, T. T. (2008). CARDIOPROTECTION BY l-GLUTAMATE DURING POSTISCHAEMIC REPERFUSION: REDUCED INFARCT SIZE AND ENHANCED GLYCOGEN RESYNTHESIS IN A RAT INSULIN-FREE HEART MODEL. Clinical and Experimental Pharmacology and Physiology. https://doi.org/10.1111/j.1440-1681.2008.04914.x

Halbirk, M., Nørrelund, H., Møller, N., Holst, J. J., Schmitz, O., Nielsen, B. R. R., Nielsen-Kudsk, J. E., Nielsen, S. S., Nielsen, T. T., Eiskjær, H., Bøtker, H. E. & Wiggers, H. (2010). Cardiovascular and metabolic effects of 48-h glucagon-like peptide-1 infusion in compensated chronic patients with heart failure. American Journal of Physiology: Heart and Circulatory Physiology, 298(3), 1096-1102.

Halbirk, M., Nørrelund, H., Møller, N., Holst, J. J., Schmitz, O., Nielsen, R., Nielsen-Kudsk, J. E., Nielsen, S. S., Toftegård, T., Eiskjær, H., Bøtker, H. E. & Wiggers, H. (2010). Cardiovascular and Metabolic Effects of 48-Hour Glucagon-like Peptide 1 Infusion in Compensated Chronic Heart Failure Patients. American Journal of Physiology: Heart and Circulatory Physiology, 298(3), H1096-102. https://doi.org/10.1152/ajpheart.00930.2009

Thangavel, S., Korsholm, K., Veien, K. T., Larsen, K. M. & Andersen, A. (2023). Catheter-directed mechanical thrombectomy in a patient with high-risk pulmonary embolism complicated by out-of-hospital cardiac arrest: A case report. European Heart Journal - Case Reports, 7(7), Article ytad307. https://doi.org/10.1093/ehjcr/ytad307

Merit, V. T., Kirk, M. E., Schultz, J. G., Hansen, J. V., Lyhne, M. D., Kramer, A. D., Pedersen, C. C. E., Karout, L., Kalra, M. K., Andersen, A. & Nielsen-Kudsk, J. E. (2024). Changes in Pulmonary Vascular Resistance and Obstruction Score Following Acute Pulmonary Embolism in Pigs. Critical care explorations, 6(2), E1040. https://doi.org/10.1097/CCE.0000000000001040

Freixa, X., Llull, L., Gafoor, S., Cruz-Gonzalez, I., Shakir, S., Omran, H., Berti, S., Santoro, G., Kefer, J., Landmesser, U., Nielsen-Kudsk, J. E., Kanagaratnam, P., Nietlispach, F., Gloekler, S., Aminian, A., Danna, P., Rezzaghi, M., Stock, F., Stolcova, M. ... Tzikas, A. (2016). Characterization of Cerebrovascular Events After Left Atrial Appendage Occlusion. The American Journal of Cardiology, 118(12), 1836-1841. https://doi.org/10.1016/j.amjcard.2016.08.075

Vij, V., Piayda, K., Nelles, D., Gloekler, S., Galea, R., Fürholz, M., Meier, B., Valgimigli, M., O'Hara, G., Arzamendi, D., Agudelo, V., Asmarats, L., Freixa, X., Flores-Umanzor, E., De Backer, O., Sondergaard, L., Nombela-Franco, L., McInerney, A., Korsholm, K. ... Sedaghat, A. (2022). Clinical and echocardiographic risk factors for device-related thrombus after left atrial appendage closure: an analysis from the multicenter EUROC-DRT registry. Clinical Research in Cardiology, 111(11), 1276-1285. https://doi.org/10.1007/s00392-022-02065-4

Nielsen-Kudsk, J. E., Korsholm, K., Damgaard, D., Valentin, J. B., Diener, H.-C., Camm, A. J. & Johnsen, S. P. (2021). Clinical Outcomes Associated With Left Atrial Appendage Occlusion Versus Direct Oral Anticoagulation in Atrial Fibrillation. JACC. Cardiovascular interventions, 14(1), 69-78. https://doi.org/10.1016/j.jcin.2020.09.051

Korsholm, K., Valentin, J. B., Damgaard, D., Diener, H.-C., Camm, A. J., Landmesser, U., Hildick-Smith, D., Johnsen, S. P. & Nielsen-Kudsk, J. E. (2022). Clinical outcomes of left atrial appendage occlusion versus direct oral anticoagulation in patients with atrial fibrillation and prior ischemic stroke: A propensity-score matched study. International Journal of Cardiology, 363, 56-63. https://doi.org/10.1016/j.ijcard.2022.06.065

Piayda, K., Hellhammer, K., Nielsen-Kudsk, J. E., Schmidt, B., Mazzone, P., Berti, S., Fischer, S., Lund, J., Montorfano, M., Della Bella, P., Gage, R. & Zeus, T. (2021). Clinical outcomes of patients undergoing percutaneous left atrial appendage occlusion in general anaesthesia or conscious sedation: data from the prospective global Amplatzer Amulet Occluder Observational Study. BMJ Open, 11(3), Article e040455. https://doi.org/10.1136/bmjopen-2020-040455

Lyhne, M. D., Schultz, J. G., Dragsbæk, S. J., Hansen, J. V., Mortensen, C. S., Kramer, A. D., Nielsen-Kudsk, J. E. & Andersen, A. (2021). Closed Chest Biventricular Pressure-Volume Loop Recordings with Admittance Catheters in a Porcine Model. Journal of Visualized Experiments, 171, Article e62661. https://doi.org/10.3791/62661

Pedersen, T. A. L., Larsen, S. H. & Nielsen-Kudsk, J. E. (2015). Closure of a patent foramen ovale in patients with platypnea-orthodeoxia: a rare and overlooked cause of dyspnoea and hypoxaemia. Scandinavian Cardiovascular Journal, 49(6), 357-360. https://doi.org/10.3109/14017431.2015.1071874

Hardt, S. E., Eicken, A., Berger, F., Schubert, S., Carminati, M., Butera, G., Grohmann, J., Höhn, R., Nielsen-Kudsk, J. E., Hildick-Smith, D., Settergren, M., Thomson, J. D., Geis, N. & Søndergaard, L. (2017). Closure of patent foramen ovale defects using GORE® CARDIOFORM septal occluder. Catheterization and Cardiovascular Interventions, 90(5), 824-829. https://doi.org/10.1002/ccd.26993

Nyboe, C., Fenger-Grøn, M., Nielsen-Kudsk, J. E. & Hjortdal, V. (2013). Closure of secundum atrial septal defects in the adult and elderly patients. European Journal of Cardio-Thoracic Surgery, 43(4), 752-757. https://doi.org/10.1093/ejcts/ezs405

White, R. J., Jerjes-Sanchez, C., Bohns Meyer, G. M., Pulido, T., Sepulveda, P., Wang, K. Y., Grünig, E., Hiremath, S., Yu, Z., Gangcheng, Z., Yip, W. L. J., Zhang, S., Khan, A., Deng, C. Q., Grover, R., Tapson, V. F. & FREEDOM-EV (2020). Combination Therapy with Oral Treprostinil for Pulmonary Arterial Hypertension: A Double-Blind Placebo-controlled Clinical Trial. American Journal of Respiratory and Critical Care Medicine, 201(6), 707-717. https://doi.org/10.1164/rccm.201908-1640OC

Seo, K., Rainer, P. P., Shalkey Hahn, V., Lee, D.-I., Jo, S.-H., Andersen, A., Liu, T., Xu, X., Willette, R. N., Lepore, J. J., Marino, J. P., Birnbaumer, L., Schnackenberg, C. G. & Kass, D. A. (2014). Combined TRPC3 and TRPC6 blockade by selective small-molecule or genetic deletion inhibits pathological cardiac hypertrophy. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1308963111

Andersen, A. (2018). Comment on "Effect of Riociguat and Sildenafil on Right Heart Remodeling and Function in Pressure Overload Induced Model of Pulmonary Arterial Banding". BioMed Research International, 2018, 6593682. Article 6593682. https://doi.org/10.1155/2018/6593682

Freixa, X., Schmidt, B., Mazzone, P., Berti, S., Fischer, S., Lund, J., Montorfano, M., Della Bella, P., Lam, S. C. C., Cruz-Gonzalez, I., Gage, R., Omran, H., Tarantini, G., Aminian, A. & Nielsen-Kudsk, J. E. (2021). Comparative data on left atrial appendage occlusion efficacy and clinical outcomes by age group in the Amplatzer™ Amulet™ Occluder Observational Study. Europace, 23(2), 238–246. https://doi.org/10.1093/europace/euaa262

Arru, C., Ebrahimian, S., Falaschi, Z., Hansen, J. V., Pasche, A., Lyhne, M. D., Zimmermann, M., Durlak, F., Mitschke, M., Carriero, A., Nielsen-Kudsk, J. E., Kalra, M. K. & Saba, L. (2021). Comparison of deep learning, radiomics and subjective assessment of chest CT findings in SARS-CoV-2 pneumonia. Clinical Imaging, 80, 58-66. https://doi.org/10.1016/j.clinimag.2021.06.036

Displaying results 51 to 100 out of 302

Revised 11.04.2023

Kristina Laut Matzen

Department of Clinical Medicine

Structural Heart

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