Publications

The structural heart disease group at Aarhus University and Aarhus University Hospital has a high level of clinical research activity. Here you can see our recent published papers.

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List of publications

Korsholm, K. K., Andersen, A., Kirkfeldt, R. E., Hansen, K. N., Mellemkjær, S. & Nielsen-Kudsk, J. E. (2015). Survival in an incident cohort of patients with pulmonary arterial hypertension in Denmark. Pulmonary Circulation, 5(2), 364-9. https://doi.org/10.1086/681270

Andersen, S., Andersen, A., de Man, F. S. & Nielsen-Kudsk, J. E. (2015). Sympathetic nervous system activation and β-adrenoceptor blockade in right heart failure. European Journal of Heart Failure. https://doi.org/10.1002/ejhf.253

Vildbrad, M. D., Andersen, A., Holmboe, S., Ringgaard, S., Nielsen, J. M. & Nielsen-Kudsk, J. E. (2014). Acute effects of levosimendan in experimental models of right ventricular hypertrophy and failure. Pulmonary Circulation, 4(3), 511-519. https://doi.org/10.1086/677366

Larsen, S. H., Emmertsen, K., Hjortdal, V. E. & Nielsen-Kudsk, J. E. (2014). Adverse Events in Transcatheter Interventions for Congenital Heart Disease: A Population-based Long-term Study. Congenital Heart Disease, 10(2), 153-158. https://doi.org/10.1111/chd.12218

Seo, K., Rainer, P. P., Shalkey Hahn, V., Lee, D.-I., Jo, S.-H., Andersen, A., Liu, T., Xu, X., Willette, R. N., Lepore, J. J., Marino, J. P., Birnbaumer, L., Schnackenberg, C. G. & Kass, D. A. (2014). Combined TRPC3 and TRPC6 blockade by selective small-molecule or genetic deletion inhibits pathological cardiac hypertrophy. Proceedings of the National Academy of Sciences (PNAS). https://doi.org/10.1073/pnas.1308963111

Kristensen, S. D., Laut, K. G., Fajadet, J., Kaifoszova, Z., Kala, P., Di Mario, C., Wijns, W., Clemmensen, P., Agladze, V., Antoniades, L., Alhabib, K. F., De Boer, M.-J., Claeys, M. J., Deleanu, D., Dudek, D., Erglis, A., Gilard, M., Goktekin, O., Guagliumi, G. ... European Association for Percutaneous Cardiovascular Interventions (2014). Corrigendum to: Reperfusion therapy for ST elevation acute myocardial infarction 2010/2011: current status in 37 ESC countries. European Heart Journal, 35(38), 2697. https://doi.org/10.1093/eurheartj/ehu333

Andersen, S., Schultz, J. G., Andersen, A., Ringgaard, S., Nielsen, J. M., Holmboe, S., Vildbrad, M. D., de Man, F. S., Bogaard, H. J., Vonk-Noordegraaf, A. & Nielsen-Kudsk, J. E. (2014). Effects of Bisoprolol and Losartan Treatment in the Hypertrophic and Failing Right Heart. Journal of Cardiac Failure, 20(11), 864-873. https://doi.org/10.1016/j.cardfail.2014.08.003

Laut, K. G., Hjort, J., Engstrøm, T., Jensen, L. O., Tilsted Hansen, H.-H., Jensen, J. S., Pedersen, F., Jørgensen, E., Holmvang, L., Pedersen, A. B., Christensen, E. F., Lippert, F., Lang-Jensen, T., Jans, H., Hansen, P. A., Trautner, S., Kristensen, S. D., Lassen, J. F., Lash, T. L. ... Terkelsen, C. J. (2014). Impact of Health Care System Delay in Patients With ST-Elevation Myocardial Infarction on Return to Labor Market and Work Retirement. The American Journal of Cardiology, 114(12), 1810-1816. https://doi.org/10.1016/j.amjcard.2014.09.018

Lyhne, M. D. & Lyhne, J. D. (2014). Improvements in CanMEDS competencies for medical students in an interdisciplinary and voluntary setting. Advances in Medical Education and Practice, 5, 499-505. Article 5. https://doi.org/10.2147/AMEP.S74876

Lewalter, T., Kanagaratnam, P., Schmidt, B., Rosenqvist, M., Nielsen-Kudsk, J. E., Ibrahim, R., Albers, B. A. & Camm, A. J. (2014). Ischaemic stroke prevention in patients with atrial fibrillation and high bleeding risk: opportunities and challenges for percutaneous left atrial appendage occlusion. EP Europace, 16(5), 626-30. https://doi.org/10.1093/europace/euu069

Heiberg, J., Hjortdal, V. E. & Nielsen-Kudsk, J. E. (2014). Long-Term Outcome after Transcatheter Closure of Postinfarction Ventricular Septal Rupture. Journal of Interventional Cardiology, 27(5), 509-515. https://doi.org/10.1111/joic.12146

Agger, P., Ilkjær, C., Laustsen, C., Smerup, M. H., Nielsen-Kudsk, J. E., Pedersen, M. & Hjortdal, V. E. (2014). Myocardial remodelling due to right ventricular dilatation in congenital heart disease. Poster session presented at PhD Day 2014, Aarhus, Denmark.

Kristensen, S. D., Laut, K. G., Fajadet, J., Kaifoszova, Z., Kala, P., Di Mario, C., Wijns, W., Clemmensen, P., Agladze, V., Antoniades, L., Alhabib, K. F., De Boer, M.-J., Claeys, M. J., Deleanu, D., Dudek, D., Erglis, A., Gilard, M., Goktekin, O., Guagliumi, G. ... On behalf of the European Association for Percutaneous Cardiovascular Interventions (2014). Reperfusion therapy for ST elevation acute myocardial infarction 2010/2011: current status in 37 ESC countries. European Heart Journal. https://doi.org/10.1093/eurheartj/eht529

Nyboe, C., Olsen, M. S., Nielsen-Kudsk, J. E., Johnsen, S. P. & Hjortdal, V. E. (2014). Risk of Pneumonia in Adults With Closed Versus Unclosed Atrial Septal Defect (from a Nationwide Cohort Study). The American Journal of Cardiology, 114(1), 105-110. https://doi.org/10.1016/j.amjcard.2014.03.063

Nielsen-Kudsk, J. E. (2014). Tromboembolisme ved atrieflimren kan forhindres ved perkutan transkateterlukning af venstre hjerteaurikel. Ugeskrift for Læger, 176(38).

Andersen, A., Nielsen, J. M., Rasalingam, S., Sloth, E. & Nielsen-Kudsk, J. E. (2013). Acute effects of sildenafil and dobutamine in the hypertrophic and failing right heart in vivo. Pulmonary Circulation, 3(3), 599-610. https://doi.org/10.1086/674327

Lauridsen, H., Andersen, A., Pedersen, M. & Ringgaard, S. (2013). Cardiac function imaging in the axolotl using a new self-gating approach. http://ismrm.org/13/

Nyboe, C., Fenger-Grøn, M., Nielsen-Kudsk, J. E. & Hjortdal, V. (2013). Closure of secundum atrial septal defects in the adult and elderly patients. European Journal of Cardio-Thoracic Surgery, 43(4), 752-757. https://doi.org/10.1093/ejcts/ezs405

Laut, K. G., Gale, C. P., Lash, T. L. & Kristensen, S. D. (2013). Determinants and patterns of utilization of primary percutaneous coronary intervention across 12 European countries: 2003-2008. International Journal of Cardiology. https://doi.org/10.1016/j.ijcard.2013.03.085

Nyboe, C., Hjortdal, V. E. & Nielsen-Kudsk, J. E. (2013). First experiences with the GORE(®) Septal Occluder in children and adults with atrial septal defects. Catheterization and Cardiovascular Interventions, 82(6), 929-34. https://doi.org/10.1002/ccd.24851

Holmboe, S., Andersen, A., Vildbrad, M. D., Nielsen, J. M., Ringgaard, S. & Nielsen-Kudsk, J. E. (2013). Iloprost improves ventricular function in the hypertrophic and functionally impaired right heart by direct stimulation. Pulmonary Circulation, 3(4), 870-9. https://doi.org/10.1086/674760

Groth, K. A., Erik Nielsen-Kudsk, J., Nørgaard, B. L. & Andersen, N. H. (2013). Internal mammary arteriovenous fistula found late after aortic root replacement. European Journal of Echocardiography, 14(8), 831. https://doi.org/10.1093/ehjci/jet025

Nyboe, C., Nielsen-Kudsk, J. E. & Hjortdal, V. (2013). Is closure of atrial septal defects in adults still controversial? European Journal of Cardio-Thoracic Surgery, 45(1), 202. https://doi.org/10.1093/ejcts/ezt298

Andersen, A. & Nielsen-Kudsk, J. E. (2013). Is the effect of cGMP modulation by phosphodiesterase-5 inhibition dependent on the magnitude of pressure overload in the hypertrophic right heart? Experimental Physiology, 98(12), 1718. https://doi.org/10.1113/expphysiol.2013.075697

Laut, K. G., Gale, C. P., Pedersen, A. B., Fox, K. A. A., Lash, T. L. & Kristensen, S. D. (2013). Persistent geographical disparities in the use of primary percutaneous coronary intervention in 120 European regions: exploring the variation. EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 9(4), 469-76. https://doi.org/10.4244/EIJV9I4A76

Andersen, C. U., Sønderskov, L. D., Nielsen-Kudsk, J. E., Simonsen, U., Bendstrup, E., Hilberg, O. & Mellemkjær, S. (2013). [Pulmonary hypertension--classification, work-up and treatment]. Ugeskrift for Læger, 175(23), 1642-1645.

Andersen, C. U., Mellemkjær, S., Nielsen-Kudsk, J. E., Bendstrup, E., Hilberg, O. & Simonsen, U. (2013). Pulmonary hypertension in chronic obstructive and interstitial lung diseases. International Journal of Cardiology, 168(3), 1795-1804. https://doi.org/10.1016/j.ijcard.2013.06.033

Andersen, A., Povlsen, J. A., Bøtker, H. E. & Nielsen-Kudsk, J. E. (2013). Right ventricular hypertrophy and failure abolish cardioprotection by ischaemic pre-conditioning. European Journal of Heart Failure. https://doi.org/10.1093/eurjhf/hft105

Nyboe, C., Olsen, M. S., Nielsen-Kudsk, J. E. & Hjortdal, V. E. (2013). Risk of pneumonia in adult patients with atrial septal defect. Abstract from The 5th Joint Scandinavian Conference in Cardiothoracic Surgery, Aarhus, Denmark.

Andersen, A., Nielsen, J. M., Holmboe, S., Vildbrad, M. D. & Nielsen-Kudsk, J. E. (2013). The Effects of Cyclic Guanylate Cyclase Stimulation on Right Ventricular Hypertrophy and Failure Alone and in Combination with Phosphodiesterase-5 Inhibition. Journal of Cardiovascular Pharmacology and Therapeutics. https://doi.org/10.1097/FJC.0b013e318294a1cf

Andersen, C. U., Mellemkjær, S., Nielsen-Kudsk, J. E., Bendstrup, E., Simonsen, U. & Hilberg, O. (2012). Diagnostic and prognostic role of biomarkers for pulmonary hypertension in interstitial lung disease. Respiratory Medicine. https://doi.org/10.1016/j.rmed.2012.09.003

Andersen, C. U., Mellemkjær, S., Nielsen-Kudsk, J. E., Sønderskov, L. D., Laursen, B. E., Simonsen, U. & Hilberg, O. (2012). Echocardiographic screening for pulmonary hypertension in stable COPD out-patients and NT-proBNP as a rule-out test. C O P D, 505. https://doi.org/10.3109/15412555.2012.695818

Kristensen, S. D., Fajadet, J., Di Mario, C., Kaifoszova, Z., Laut, K. G., Deleanu, D., Gilard, M., Guagliumi, G., Goktekin, O., Jorgova, J., Kanakakis, J., Ostojic, M., Pereira, H., Sabate, M., Sobhy, M., Vrints, C., Wijns, W. & Widimsky, P. (2012). Implementation of primary angioplasty in Europe: stent for life initiative progress report. EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 8(1), 35-42. https://doi.org/10.4244/EIJV8I1A7

Andersen, A., Povlsen, J. A., Bøtker, H. E. & Nielsen-Kudsk, J. E. (2012). Ischemia and ischemic preconditioning in the hypertrophic and failing right heart. Abstract from PCCS 2013, Cape Town.

Andersen, A., Povlsen, J. A., Bøtker, H. E. & Nielsen-Kudsk, J. E. (2012). Ischemic Preconditioning Reduces Right Ventricular Infarct Size through Opening of Mitochondrial Potassium Channels. Cardiology (Switzerland), 123(3), 177-80. https://doi.org/10.1159/000342481

Andersen, K. H., Iversen, M. J., Kjaergaard, J., Mortensen, J., Nielsen-Kudsk, J. E., Bendstrup, E., Videbaek, R. & Carlsen, J. (2012). Prevalence, predictors, and survival in pulmonary hypertension related to end-stage chronic obstructive pulmonary disease. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 31(4), 373–380. https://doi.org/10.1016/j.healun.2011.11.020

Andersen, C. U., Mellemkjær, S., Hilberg, O., Nielsen-Kudsk, J. E., Simonsen, U. & Bendstrup, E. (2012). Pulmonary hypertension in interstitial lung disease: Prevalence, prognosis and 6 min walk test. Respiratory Medicine, 106(6), 875–882. https://doi.org/10.1016/j.rmed.2012.02.015

Andersen, A., Povlsen, J. A., Bøtker, H. E. & Nielsen-Kudsk, J. E. (2012). Right ventricular hypertrophy and failure abolish cardioprotection by ischemic preconditioning. Poster session presented at ESC Congress 2012, Munchen, Germany.

Laut, K. G. & Foldspang, A. (2012). The effects on length of stay of introducing a fast track patient pathway for myocardial infarction: a before and after evaluation. Health Services Management Research, 25(1), 31-4. https://doi.org/10.1258/hsmr.2011.011021

Andersen, A., Nielsen, J. M., Holmboe, S., Vildbrad, M. D. & Nielsen-Kudsk, J. E. (2012). The guanylate cyclase stimulator BAY 41-2272 does not prevent right ventricular hypertrophy and failure alone or in combination with sildenafil.

Andersen, C. U., Hilberg, O., Mellemkjær, S., Nielsen-Kudsk, J. E. & Simonsen, U. (2011). Apelin and pulmonary hypertension. Pulmonary Circulation, 1(3), 334-46. https://doi.org/10.4103/2045-8932.87299

Laut, K. G., Pedersen, A. B., Lash, T. & Kristensen, S. D. (2011). Barriers to Implementation of Primary Percutaneous Coronary Intervention in Europe. European Cardiology, 7(2), 108-112. http://www.touchcardiology.com/journals/editions/european-cardiology-volume-7-issue-2