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Department of Clinical Medicine

Comparative Medicine Lab

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Vammen, L., Munch Johannsen, C., Magnussen, A., Povlsen, A. L., Riis Petersen, S., Azizi, A., Pedersen, M., Korshoej, A. R., Ringgaard, S., Løfgren, B., Andersen, L. W. & Granfeldt, A. (2022). Cerebral monitoring in a pig model of cardiac arrest with 48 h of intensive care. Intensive Care Medicine Experimental, 10(1), Article 45. https://doi.org/10.1186/s40635-022-00475-2

Dalsgaard, F. F., Moeslund, N., Zhang, Z. L., Pedersen, M., Qerama, E., Beniczky, S., Ryhammer, P., Ilkjær, L. B., Erasmus, M. & Eiskjær, H. (2022). Clamping of the Aortic Arch Vessels During Normothermic Regional Perfusion After Circulatory Death Prevents the Return of Brain Activity in a Porcine Model. Transplantation, 106(9), 1763-1769. https://doi.org/10.1097/TP.0000000000004047

Thygesen, M. M., Lund, T. E., Mikkelsen, I. K., Kasch, H., Dalby, R. B., Dyrskog, S. E., Pedersen, M. & Rasmussen, M. M. (2022). Correction to: Diffusional kurtosis imaging as a possible prognostic marker of cervical incomplete spinal cord injury outcome: a prospective pilot study (Acta Neurochirurgica, (2022), 164, 1, (25-32), 10.1007/s00701-021-05018-4). Acta Neurochirurgica, 164(1), 33. https://doi.org/10.1007/s00701-021-05053-1

Greibe, E., Leth-Møller, M., Stampe, S. R., Ovesen, P. G., Pedersen, M. & Hoffmann-Lücke, E. (2022). Development and validation of an LC-MS/MS method for the quantification of artificial sweeteners in human matrices. Biomedical Chromatography, 36(6), Article e5350. https://doi.org/10.1002/bmc.5350

Thygesen, M., Lund, T. E., Mikkelsen, I. K., Kasch, H., Dalby, R. B., Dyrskog, S. E., Pedersen, M. & Rasmussen, M. M. (2022). Diffusional kurtosis imaging as a possible prognostic marker of cervical incomplete spinal cord injury outcome: a prospective pilot study. Acta Neurochirurgica, 164(1), 25-32. https://doi.org/10.1007/s00701-021-05018-4

Dittrich, A., Andersson, S. A., Busk, M., Nielsen, R. J. & Lauridsen, H. (2022). Does Metabolism Regulate Cardiac Repair in the Regeneration Competent Axolotl Salamander? The FASEB Journal, 36(S1). https://doi.org/10.1096/fasebj.2022.36.S1.R1919

Munk, A., Duvald, C. S., Pedersen, M., Lohmann, S., Keller, A. K., Møller, B. K., Ringgaard, S., Buus, N. H., Jespersen, B. & Eijken, M. (2022). Dosing Limitation for Intra-Renal Arterial Infusion of Mesenchymal Stromal Cells. International Journal of Molecular Sciences , 23(15), Article 8268. https://doi.org/10.3390/ijms23158268

Lauridsen, H., Thøstesen, C. B., Pedersen, C. C. E., Ringgaard, S., Steeman, M., Møller, P. R., Johansson, D. K. & Alstrup, A. K. O. (2022). Heterochronic maturation of anatomical plugs for protecting the airway in rorqual whales (Balaenopteridae). Royal Society Open Science, 9(12), 1-7. Article 220459. https://doi.org/10.1098/rsos.220459

Moeslund, N., Long Zhang, Z., Bo Ilkjaer, L., Ryhammer, P. K., Cramer, C., Palmfeldt, J., Pedersen, M., Erasmus, M. E., Tsui, S. & Eiskjaer, H. (2022). High Oxygenation During Normothermic Regional Perfusion After Circulatory Death Is Beneficial on Donor Cardiac Function in a Porcine Model. Transplantation, 106(7), e326-e335. https://doi.org/10.1097/TP.0000000000004164

Hansen, K., Hansen, E. S. S., Jespersen, N. R. V., Bøtker, H. E., Pedersen, M., Wang, T. & Laustsen, C. (2022). Hyperpolarized ¹³C MRI Reveals Large Changes in Pyruvate Metabolism During Digestion in Snakes. Magnetic Resonance in Medicine, 88(2), 890-900. https://doi.org/10.1002/mrm.29239

Nielsen, T. H., Rasmussen, M. M. & Thygesen, M. M. (2022). Incidence and risk factors for incidental durotomy in spine surgery for lumbar stenosis and herniated disc. Acta Neurochirurgica, 164(7), 1883-1888. https://doi.org/10.1007/s00701-022-05259-x

Leth Bergholt, N., Demirel, A., Pedersen, M., Ding, M., Kragstrup, T. W., Andersen, T., Deleuran, B. W. & Foldager, C. B. (2022). Intermittent hypoxic therapy inhibits allogenic bone-graft resorption by inhibition of osteoclastogenesis in a mouse model. International Journal of Molecular Sciences , 23(1), Article 323. https://doi.org/10.3390/ijms23010323

MacIver, D. H., Agger, P., Rodrigues, J. C. L. & Zhang, H. (2022). Left ventricular active strain energy density is a promising new measure of systolic function. Scientific Reports, 12(1), Article 12717. https://doi.org/10.1038/s41598-022-15509-8

Andersson, S. A., Dittrich, A. & Lauridsen, H. (2022). Long-term Anesthesia in the Mexican Axolotl Salamander. The FASEB Journal, 36(S1). https://doi.org/10.1096/fasebj.2022.36.S1.R1917

Moeslund, N., Ryhammer, P. K., Ilkjær, L. B., Pedersen, M. & Eiskjær, H. (2022). Normothermic regional perfusion of circulatory dead donor hearts: quick and dirty or slow and steady? The Journal of Heart and Lung Transplantation, 41(4, Supplement), S239. https://doi.org/10.1016/j.healun.2022.01.1739

Andersson, S. A., Thygesen, M., Dittrich, A. & Lauridsen, H. (2022). One Week of Continuous Anesthesia by Propofol (2,6-Diisopropylphenol) Does Not Cause Neurobehavioral Changes after Recovery in the Mexican Axolotl Salamander. OBM Neurobiology, 6(3), Article 7. https://doi.org/10.21926/obm.neurobiol.2203127

Meyer, S., Lauridsen, H., Pedersen, K., Andersson, S. A., van Ooij, P., Willems, T., Berger, R. M. F., Ebels, T. & Jensen, B. (2022). Opportunities and short-comings of the axolotl salamander heart as a model system of human single ventricle and excessive trabeculation. Scientific Reports, 12(1), Article 20491. https://doi.org/10.1038/s41598-022-24442-9

Jakobsen, S. R., Borg Hansen, I., Harders, S. W., Thomsen, A. H., Pedersen, C. C. E., Boel, L. W. T. & Hansen, K. (2022). Quantitative analysis of pulmonary structures in PMCT; Stereological comparison of drowning compared to opioid-overdose cases. Forensic Imaging, 28, Article 200486. https://doi.org/10.1016/j.fri.2022.200486

Kerrn-Jespersen, S., Andersen, M., Bennedsgaard, K., Andelius, T. C. K., Pedersen, M., Kyng, KJ. & Henriksen, T. B. (2022). Remote ischemic postconditioning increased cerebral blood flow and oxygenation assessed by magnetic resonance imaging in newborn piglets after hypoxia-ischemia. Frontiers in Pediatrics, 10, Article 933962. https://doi.org/10.3389/fped.2022.933962

Ahring, K. K., Dagnæs-Hansen, F., Brüel, A., Christensen, M., Jensen, E., Jensen, T. G., Johannsen, M., Johansen, K. S., Lund, A. M., Madsen, J. G., Brøndum-Nielsen, K., Pedersen, M., Sørensen, L. K., Kjolby, M. & Møller, L. B. (2022). The effect of casein glycomacropeptide versus free synthetic amino acids for early treatment of phenylketonuria in a mice model. PLOS ONE, 17(1), Article e0261150. https://doi.org/10.1371/journal.pone.0261150

Christiansen, K. J., Devantier, L., Pasgaard, T., Benson, T. E., Petersen, J. J., Kjærgaard, T. & Pedersen, M. (2022). Tracheostomy healing time after decannulation. Multidisciplinary Respiratory Medicine, 17(1), Article 822. https://doi.org/10.4081/mrm.2022.822

Larsen, C. G., Karlberg, M., Guldfred, F., Devantier, L., Maagaard, M., Homøe, P. & Djurhuus, B. D. (2022). Transmyringeal ventilation tube insertion for unilateral Menière’s disease: a protocol for a prospective, sham-controlled, double-blinded, randomized, clinical trial. Trials, 23(1), Article 877. https://doi.org/10.1186/s13063-022-06777-w

Damsgaard, C., Lauridsen, H., Harter, T., Kwan, G., Thomsen, J., Funder, A., Supuran, C., Tresguerres, M., Matthews, P. & Brauner, C. (2021). Active Blood Acidification Greatly Enhances Oxygen Supply to the Teleost Retina. FASEB Journal, 35. https://doi.org/10.1096/fasebj.2021.35.S1.01833

Hansen, K. (2021). A detachable tourniquet to aid rodent tail-vasculature catheterisation; especially useful for preclinical imaging. Scandinavian Journal of Laboratory Animal Science, 47(6), 42-44. https://doi.org/10.23675/sjlas.v47i0.1088

Thygesen, M., Nielsen, T. D., Rasmussen, M., Orlowski, D., Pedersen, M. & Rasmussen, M. M. (2021). A review of spinal cord perfusion pressure guided interventions in traumatic spinal cord injury. European Spine Journal, 30(10), 3028-3035. https://doi.org/10.1007/s00586-021-06905-1

Møller, P. R., Schwarzhans, W. W., Lauridsen, H. & Nielsen, J. G. (2021). Bidenichthys okamotoi, a new species of the Bythitidae (Ophidiiformes, Teleostei) from the Koko Seamount, Central North Pacific. Journal of Marine Science and Engineering, 9(12), Article 1399. https://doi.org/10.3390/jmse9121399

Pedersen, K., Rasmussen, R. K., Dittrich, A. & Lauridsen, H. (2021). Cardiac regeneration in the axolotl is unaffected by alterations in leukocyte numbers induced by lipopolysaccharide and prednisolone. BMC Research Notes, 14(1), Article 157. https://doi.org/10.1186/s13104-021-05574-z

Frommel, A. Y., Kwan, G. T., Prime, K. J., Tresguerres, M., Lauridsen, H., Val, A. L., Goncalves, L. U. & Brauner, C. J. (2021). Changes in gill and air‐breathing organ characteristics during the transition from water ‐ to air‐breathing in juvenile Arapaima gigas. Journal of Experimental Zoology. Part A: Ecological and Integrative Physiology , 335(9-10), 801-813. https://doi.org/10.1002/jez.2456

Devantier, L., Hansen, A. K., Mølby-Henriksen, J.-J., Pedersen, M., Borghammer, P., Ovesen, T. & Magnusson, M. (2021). Cortical Activity During an Attack of Ménière's Disease—A Case Report. Frontiers in Neurology, 12, Article 669390. https://doi.org/10.3389/fneur.2021.669390, https://doi.org/10.3389/fneur.2021.669390

Dittrich, A. & Lauridsen, H. (2021). Cryo-injury Induced Heart Regeneration in the Axolotl and Echocardiography and Unbiased Quantitative Histology to Evaluate Regenerative Progression. Journal of Visualized Experiments, 171(171), Article e61966. https://doi.org/10.3791/61966

Hansen, K. & Morgan, B. (2021). Current advances in CT imaging of the deceased lung. Current Opinion in Physiology, 22, Article 100436. https://doi.org/10.1016/j.cophys.2021.04.005

Damsgaard, C. & Lauridsen, H. (2021). Deep vascular imaging in the eye with flow-enhanced ultrasound. Journal of Visualized Experiments, 176(176), Article e62986. https://doi.org/10.3791/62986

Grønlund, C., Lembeck, M. A., Devantier, L., Lindelof, M. & Djurhuus, B. D. (2021). Den episodisk svimle patient. Ugeskrift for Læger, 183(15). https://ugeskriftet.dk/videnskab/den-episodisk-svimle-patient

Irrera, P., Consolino, L., Dastrù, W., Pedersen, M., Zöllner, F. G. & Longo, D. L. (2021). Dynamic Contrast Enhanced (DCE) MRI-Derived Renal Perfusion and Filtration: Experimental Protocol. In A. Pohlmann & T. Niendorf (Eds.), Methods in Molecular Biology: Methods and Protocols (pp. 429-441). Humana Press. https://doi.org/10.1007/978-1-0716-0978-1_25

Pedersen, M., Irrera, P., Dastrù, W., Zöllner, F. G., Bennett, K. M., Beeman, S. C., Bretthorst, G. L., Garbow, J. R. & Longo, D. L. (2021). Dynamic Contrast Enhancement (DCE) MRI-Derived Renal Perfusion and Filtration: Basic Concepts. In A. Pohlmann & T. Niendorf (Eds.), Methods in Molecular Biology: Methods and Protocols (Vol. 2216, pp. 205-227). Humana Press. https://doi.org/10.1007/978-1-0716-0978-1_12

Khatir, D. S., Carlsen, R. K., Ivarsen, P., Jespersen, B., Pedersen, M., Lodberg, K. & Buus, N. H. (2021). Effects of enhanced versus reduced vasodilating treatment on brachial and central blood pressure in patients with chronic kidney disease: a randomized controlled trial. Journal of Hypertension, 39(11), 2232-2240. https://doi.org/10.1097/HJH.0000000000002942

Moeslund, N., Zhang, Z. L., Ryhammer, P. K., Ilkjær, L. B., Pedersen, M., Erasmus, M., Tsui, S. & Eiskjær, H. (2021). High Oxygen is Likely to be Beneficial on Cardiac Contractility after Normothermic Regional Perfusion after Circulatory Death in a Porcine Model. The Journal of Heart and Lung Transplantation, 40(4), 235. https://doi.org/10.1016/j.healun.2021.01.676

Madsen, J. G., Skov, M. N., Hansen, K., Laustsen, C., Ejskjær, N., Andersen, H. & Pedersen, M. (2021). Hyperbaric Oxygen Treatment for Diabetic Retinopathy and Neuropathy in a Streptozotocin Induced Diabetic Rat Model. Journal of Biomedical Science and Engineering, 14(12), 391-401. https://doi.org/10.4236/jbise.2021.1412033

Moeslund, N., Zhang, Z. L., Dalsgaard, F. F., Glenting, S. B., Ryhammer, P. K., Ilkjær, L. B., Pedersen, M. & Eiskjær, H. (2021). Improvement of Left but Not Right Ventricular Contractility after Circulatory Death and Normothermic Regional Perfusion in a Porcine Model. The Journal of Heart and Lung Transplantation, 40(4), S234-S235. Article 560. https://doi.org/10.1016/j.healun.2021.01.674

Hyldebrandt, J. A., Bøgh, N., Omann, C. & Agger, P. (2021). Norepinephrine and dobutamine improve cardiac index equally by supporting opposite sides of the heart in an experimental model of chronic pulmonary hypertension. Intensive Care Medicine Experimental, 9(1), Article 29. https://doi.org/10.1186/s40635-021-00391-x

Christensen, B. B., Olesen, M. L., Hede, K. T. C., Bergholt, N. L., Foldager, C. B. & Lind, M. (2021). Particulated Cartilage for Chondral and Osteochondral Repair: A Review. Cartilage, 13(1suppl), 1047S-1057S. https://doi.org/10.1177/1947603520904757

Kyng, K. J., Kerrn-Jespersen, S., Bennedsgaard, K., Skajaa, T., Pedersen, M., Holm, I. E. & Henriksen, T. B. (2021). Short-term outcomes of remote ischemic postconditioning 1 h after perinatal hypoxia-ischemia in term piglets. Pediatric Research, 89(1), 150-156. https://doi.org/10.1038/s41390-020-0878-6

Bromer, F. D., Brent, M. B., Pedersen, M., Thomsen, J. S., Brüel, A. & Foldager, C. B. (2021). The Effect of Normobaric Intermittent Hypoxia Therapy on Bone in Normal and Disuse Osteopenic Mice. High Altitude Medicine and Biology, 22(2), 225-234. https://doi.org/10.1089/ham.2020.0164

Williams, C. J. A., Hansen, K., Williams, N., Jakobsen, S. R., Pedersen, C. C. E., Bertelsen, M. F. & Wang, T. (2021). The influence of assisted ventilation and recumbency on cardiorespiratory physiology in the anesthetized freshwater turtle Trachemys scripta scripta. Comparative Biochemistry and Physiology -Part A : Molecular and Integrative Physiology, 260, Article 111036. https://doi.org/10.1016/j.cbpa.2021.111036

Hansen, E. S. S., Madsen, T. L., Wood, G., Granfeldt, A., Bøgh, N., Tofig, B. J., Agger, P., Lindhardt, J. L., Poulsen, C. B., Bøtker, H. E. & Kim, W. Y. (2021). Veno-occlusive unloading of the heart reduces infarct size in experimental ischemia-reperfusion. Scientific Reports, 11(1), Article 4483. https://doi.org/10.1038/s41598-021-84025-y

Brogård Andersen, H., Andersen, M., Andelius, T. C. K., Pedersen, M. V., Løfgren, B., Pedersen, M., Ringgaard, S., Kyng, KJ. & Henriksen, T. B. (2020). Adrenaline versus placebo during resuscitation – the effect on ROSC and markers of CNS outcome; a newborn piglet model of hypoxic cardiac arrest. Poster session presented at 8th Congress of the European Academy of Paediatric Societies (virtuel).

Hansen, K., Machin, R., James, J., Coats, T. & Rutty, G. N. (2020). A look inside cardiopulmonary resuscitation: A 4D computed tomography model of simulated closed chest compression. A proof of concept. Resuscitation, 153, 149-153. https://doi.org/10.1016/j.resuscitation.2020.05.037

Agger, P., Omann, C., Laustsen, C., Stephenson, R. S. & Anderson, R. H. (2020). Anatomically correct assessment of the orientation of the cardiomyocytes using diffusion tensor imaging. NMR in Biomedicine, 33(3), Article e4205. https://doi.org/10.1002/nbm.4205

Damsgaard, C., Lauridsen, H., Harter, T. S., Kwan, G. T., Thomsen, J. S., Funder, A. M. D., Supuran, C. T., Tresguerres, M., Matthews, P. GD. & Brauner, C. J. (2020). A novel acidification mechanism for greatly enhanced oxygen supply to the fish retina. eLife, 9, 1-20. Article e58995. https://doi.org/10.7554/eLife.58995

Agger, P. & Stephenson, R. S. (2020). Assessing Myocardial Architecture: The Challenges and Controversies. Journal of Cardiovascular Development and Disease, 7(4), 1-17. Article 47. https://doi.org/10.3390/jcdd7040047

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Maria Ditlev