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Department of Clinical Medicine

Infectious Diseases

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Prabakaran, T., Troldborg, A., Kumpunya, S., Alee, I., Marinković, E., Windross, S. J., Nandakumar, R., Narita, R., Zhang, B.-C., Carstensen, M., Vejvisithsakul, P., Marqvorsen, M. H. S., Iversen, M. B., Holm, C. K., Østergaard, L. J., Pedersen, F. S., Pisitkun, T., Behrendt, R., Pisitkun, P. & Paludan, S. R. (2021). A STING antagonist modulating the interaction with STIM1 blocks ER-to-Golgi trafficking and inhibits lupus pathology. EBioMedicine, 66, Article 103314. https://doi.org/10.1016/j.ebiom.2021.103314

Bastard, P., Gervais, A., Le Voyer, T., Rosain, J., Philippot, Q., Manry, J., Michailidis, E., Hoffmann, H. H., Eto, S., Garcia-Prat, M., Bizien, L., Parra-Martínez, A., Yang, R., Haljasmägi, L., Migaud, M., Särekannu, K., Maslovskaja, J., Prost, N. D., Tandjaoui-Lambiotte, Y. ... Imagine COVID Group (2021). Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths. Science Immunology, 6(62), Article 4340. https://doi.org/10.1126/sciimmunol.abl4340

Breining, P., Frølund, A. L., Højen, J. F., Gunst, J. D., Staerke, N. B., Sædder, E. A., Cases-Thomas, M., Little, P., Nielsen, L. P., Søgaard, O. S. & Kjolby, M. (2021). Camostat mesylate against SARS-CoV-2 and COVID-19-Rationale, dosing and safety. Basic & Clinical Pharmacology & Toxicology, 128(2), 204-212. https://doi.org/10.1111/bcpt.13533

Hoffmann, M., Hofmann-Winkler, H., Smith, J. C., Krüger, N., Arora, P., Sørensen, L. K., Søgaard, O. S., Hasselstrøm, J. B., Winkler, M., Hempel, T., Raich, L., Olsson, S., Danov, O., Jonigk, D., Yamazoe, T., Yamatsuta, K., Mizuno, H., Ludwig, S., Noé, F. ... Pöhlmann, S. (2021). Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity. EBioMedicine, 65, Article 103255. https://doi.org/10.1016/j.ebiom.2021.103255

Corley, M. J., Pang, A. P. S., Rasmussen, T. A., Tolstrup, M., Søgaard, O. S. & Ndhlovu, L. C. (2021). Candidate host epigenetic marks predictive for HIV reservoir size, responsiveness to latency reversal, and viral rebound. AIDS, 35(14), 2269-2279. https://doi.org/10.1097/QAD.0000000000003065

Iversen, B. R., Rodkjær, L. Ø., Bregnballe, V. & Løkke, A. (2021). Clinical Outcome of a Cross-Sectorial Lung Team Treating Patients with COPD at High Risk of Exacerbation: A Randomized Controlled Trial. International Journal of Chronic Obstructive Pulmonary Disease, 18(2), 201-209. https://doi.org/10.1080/15412555.2021.1898577

Verholt, A. B., Gregersen, M., Bofill, N. G., Kjærskov Hansen, T., Ebdrup, L., Foss, A.-C. H. & Lietzen, L. W. (2021). Clinical presentation and outcomes of COVID 19 in older hospitalised patients assessed by the record based Multidimensional Prognostic Index. Abstract from 16th International Congress of the European Union Geriatric Medicine Society , Athens, Greece.

Verholt, A. B., Gregersen, M., Gonzalez-Bofill, N., Hansen, T. K., Ebdrup, L., Foss, A.-C. H. & Lietzen, L. W. (2021). Clinical presentation and outcomes of COVID-19 in older hospitalised patients assessed by the record-based multidimensional prognostic index, a cross-sectional study. European Geriatric Medicine, 12(6), 1147-1157. https://doi.org/10.1007/s41999-021-00522-3

Paludan, S. R. & Mogensen, T. H. (2021). Constitutive and latent immune mechanisms exert ‘silent’ control of virus infections in the central nervous system. Current Opinion in Immunology, 72, 158-166. https://doi.org/10.1016/j.coi.2021.05.004

Paludan, S. R., Pradeu, T., Masters, S. L. & Mogensen, T. H. (2021). Constitutive immune mechanisms: mediators of host defence and immune regulation. Nature Reviews Immunology, 21(3), 137-150. https://doi.org/10.1038/s41577-020-0391-5

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Lotte Bjerregaard Snabe