Understanding the structure of an organ or a tissue is the keystone to understanding its function. Thus, anatomy is the foundation of all other biomedical sciences. Using a variety of sophisticated imaging techniques this section of Comparative Medicine Lab investigates the three dimensional macro- and micro-anatomy of human and animal tissues. Previously, mainly two-dimensional tissue destructive techniques such as histology and dissection have been used for anatomical investigations resulting in inaccurate and often downright wrong conclusions. We aim at resolving these controversies and provide accurate descriptions of tissue architecture in both health and disease.