Stimulation of the Dorsal Genital Nerve (DGN) is a promising and emerging treatment for both OAB and BD. Research has demonstrated a reduction in incontinence episodes in 79% of patients with OAB using a percutaneous placed electrode for 1 week. Another study showed that by using 30 seconds of on-demand stimulation in patients with OAB allowed the patients to reach the toilet before leaking elsewhere. Further, it was shown that DGN stimulation led to increased bladder capacity and reduction in incontinence episodes. Similar, research has demonstrated a significant reduction in number of fecal incontinence episodes, together with a significant decrease in the overall number of bowel movements both with and without urgency in BD patients utilizing 2x15 minutes DGN stimulation per day. The improvement in symptoms was still present 3 weeks after stimulation.
DGN stimulation has the advantage over similar neuromodulation as it can be applied externally at the genitals allowing easy application and removal. Other devices often require surgical implantation, which has a higher cost and carries greater risk of complications. DGN stimulation has never been implemented clinically, as no acceptable electrodes specifically designed for DGN stimulation exists. Therefore, a device which can treat OAB and BD by activating DGN by external stimulation will bring more affordable and less invasive treatment options for the patients.
A total of 40 participants ≥ 18 years of age showing symptoms of OAB/BD are to receive the treatment (plaster stimulation at the root of penis/clitoris). 6 weeks treatment. Frequency volume chart and questionnaires.
The project is done as a collaboration between Department of surgery, urogynecology and urology in Pelvic Floor Unit