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Department of Clinical Medicine

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Mikkelsen, R., Andreasen, M. & Nedergaard, S. (2013). Suppression of epileptiform activity by a single short-duration electric field in rat hippocampus in vitro. Journal of Neurophysiology, 109(11), 2720-31. https://doi.org/10.1152/jn.00887.2012

Østergaard, L., Aamand, R., Gutiérrez Jiménez, E., Ho, Y. C. L., Blicher, J., Madsen, S. M., Nagenthiraja, K., Dalby, R. B., Drasbek, K. R., Møller, A., Brændgaard, H., Mouridsen, K., Jespersen, S. N., Jensen, M. S. & West, M. J. (2013). The capillary dysfunction hypothesis of Alzheimer's disease. Neurobiology of Aging, 34(4), 1018-31. https://doi.org/10.1016/j.neurobiolaging.2012.09.011

Østergaard, L., Tietze, A., Nielsen, T., Drasbek, K. R., Mouridsen, K., Jespersen, S. N. & Horsman, M. R. (2013). The relationship between tumor blood flow, angiogenesis, tumor hypoxia, and aerobic glycolysis. Cancer Research, 73(18), 5618-5624. https://doi.org/10.1158/0008-5472.CAN-13-0964

Østergaard, L., Aamand, R., Karabegovic, S., Tietze, A., Blicher, J. U., Mikkelsen, I. K., Iversen, N. K., Secher, N., Engedal, T. S., Anzabi, M., Jimenez, E. G., Cai, C., Koch, K. U., Næss-Schmidt, E. T., Obel, A., Juul, N., Rasmussen, M. & Sørensen, J. C. H. (2013). The role of the microcirculation in delayed cerebral ischemia and chronic degenerative changes after subarachnoid hemorrhage. Journal of Cerebral Blood Flow and Metabolism, 33(12), 1825-37. https://doi.org/10.1038/jcbfm.2013.173

Mortensen, M. B., Sivesgaard, K., Jensen, H. K., Comuth, W., Kanstrup, H., Gotzsche, O., May, O., Bertelsen, J. & Falk, E. (2013). Traditional SCORE-based health check fails to identify individuals who develop acute myocardial infarction. Danish Medical Journal, 60(5), A4629.

Nielsen, T., Nielsen, N. C., Holm, T. H., Ostergaard, L., Horsman, M. R. & Busk, M. (2013). Ultra-high field (1)H magnetic resonance imaging approaches for acute hypoxia. Acta Oncologica, 52(7), 1287-1292. https://doi.org/10.3109/0284186X.2013.824608

Hermitte, L., Cho, T.-H., Ozenne, B., Nighoghossian, N., Mikkelsen, I. K., Ribe, L., Baron, J.-C., Østergaard, L., Derex, L., Hjort, N., Fiehler, J., Pedraza, S., Hermier, M., Maucort-Boulch, D. & Berthezène, Y. (2013). Very Low Cerebral Blood Volume Predicts Parenchymal Hematoma in Acute Ischemic Stroke. Stroke; a journal of cerebral circulation, 44(8), 2318-2320. https://doi.org/10.1161/STROKEAHA.113.001751

Nørgaard, C., Graumann, O., Bollen, P. & Lauridsen, H. H. (2013). Videopodcasts in a “blended learning” approach to medical skills training. http://www.amee.org/getattachment/Conferences/AMEE-Past-Conferences/AMEE-Conference-2013/AMEE-2013-ABSTRACT-BOOK-updated-190813.pdf

Kallehauge, J. F., Nielsen, T., Haack, S., Peters, D. A., Mohamed, S., Fokdal, L., Lindegaard, J. C., Hansen, D. C., Rasmussen, F., Tanderup, K. & Pedersen, E. M. (2013). Voxelwise comparison of perfusion parameters estimated using dynamic contrast enhanced (DCE) computed tomography and DCE-magnetic resonance imaging in locally advanced cervical cancer. Acta Oncologica, 52(7), 1360-8. https://doi.org/10.3109/0284186X.2013.813637

Aagaard, R., Grove, E., Mikkelsen, R., Wolff, A., Iversen, K. W. & Løfgren, B. (2013). Where is the AED? Limited public ability to recognize and understand the universal ILCOR sign for AEDs: Circulation 2013 128:22 SUPPL. 1 .

Larsen, E. K. U., Nielsen, T., Wittenborn, T., Rydtoft, L. M., Lokanathan, A. R., Hansen, L., Østergaard, L., Kingshott, P., Howard, K. A., Besenbacher, F., Nielsen, N. C. & Kjems, J. (2012). Accumulation of magnetic iron oxide nanoparticles coated with variably sized polyethylene glycol in murine tumors. Nanoscale, 4(7), 2352-2361 . https://doi.org/10.1039/C2NR11554A

Nagenthiraja, K., Ribe, L. R., Hougaard, K. D., Østergaard, L. & Mouridsen, K. (2012). A Fully Automated Penumbra Segmentation Tool.

Weber, U., Lambert, R. G., Rufibach, K., Maksymowych, W. P., Hodler, J., Zejden, A., Duewell, S., Kissling, R. O., Filipow, P. L. & Jurik, A. G. (2012). Anterior chest wall inflammation by whole body MRI in patients with spondyloarthritis: lack of association between clinical and imaging findings in a cross-sectional study. Arthritis research & therapy, 14(1), R3. https://doi.org/10.1186/ar3551

Campbell, B. C. V., Tu, H. T. H., Christensen, S., Desmond, P. M., Levi, C. R., Blandin, C. F., Hjort, N., Ashkanian, M., Sølling, C., Donnan, G. A., Davis, S. M., Østergaard, L. & Parsons, M. W. (2012). Assessing Response to Stroke Thrombolysis: Validation of 24-Hour Multimodal Magnetic Resonance Imaging. Archives of Neurology, 69(1), 46-50. https://doi.org/10.1001/archneurol.2011.232

Haack, S., Pedersen, E. M., Vinding, M. S., Kallehauge, J., Lindegaard, J. C., Tanderup, K. & Jespersen, S. N. (2012). B0-correction and k-means clustering for accurate and automatic identification of regions with reduced apparent diffusion coefficient (ADC) in adva nced cervical cancer at the time of brachytherapy. Poster session presented at ISMRM 20TH Annual Meeting & Exhibition, Melbourne, Australia.

Donahue, M., Stagg, C., O'Shea, J., Jezzard, P., Østergaard, L., MacIntosh, B., Johansen-Berg, H. & Blicher, J. (2012). BOLD, CBF, and CBV fMRI measurements in chronic stroke patients reveal details of altered neurovascular coupling. Abstract from ISMRM 2012, Melbourne, Australia.

Graumann, O., Osther, S. S., Hørlyck, A. & Osther, P. J. S. (2012). Bosniak Classification system - Interobserver agreement between three radiologists.

Graumann, O., Osther, S. S., Hørlyck, A. & Osther, P. J. S. (2012). Bosniak Classification system - Interobserver agreement between three radiologists.

Graumann, O., Osther, S. S. & Osther, P. J. S. (2012). Bosniak Classification System: Usefulness of Contrast enhanced Ultrasonography.

Graumann, O., Osther, S. S. & Osther, P. J. S. (2012). Can Contrast enhanced Ultrasound (CEUS) differentiate between Benign and Malignant complex Renal Cysts?.

Brodtmann, A., Pardoe, H., Li, Q., Lichter, R., Østergaard, L. & Cumming, T. (2012). Changes in regional brain volume three months after stroke. Journal of the Neurological Sciences, 322(1-2), 122-8. https://doi.org/10.1016/j.jns.2012.07.019

Nielsen, T., Bentzen, L., Pedersen, M. N., Tramm, T., Rijken, P. F. J. W., Bussink, J., Horsman, M. R. & Østergaard, L. (2012). Combretastatin A-4 phosphate affects tumor vessel volume and size distribution as assessed using MRI-based vessel size imaging. Clinical Cancer Research, 18(23), 6469-77. https://doi.org/10.1158/1078-0432.CCR-12-2014

Dalby, R. B., Frandsen, J., Mallar, C., Ahdidan, J., Sørensen, L., Rosenberg, R., Østergaard, L. & Videbech, P. (2012). Correlations between Stroop task performance and white matter lesion measures in late-onset major depression. Psychiatry Research, 202(2), 142-149. https://doi.org/10.1016/j.pscychresns.2011.12.009

Uwano, I., Kudo, K., Sasaki, M., Christensen, S., Østergaard, L., Ogasawara, K. & Ogawa, A. (2012). CT and MR perfusion can discriminate severe cerebral hypoperfusion from perfusion absence: evaluation of different commercial software packages by using digital phantoms. Neuroradiology, 54(5), 467-74. https://doi.org/10.1007/s00234-011-0905-8

Hermann, K.-G. A., Baraliakos, X., van der Heijde, D. M. F. M., Jurik, A. G., Landewé, R., Marzo-Ortega, H., Østergaard, M., Rudwaleit, M., Sieper, J., Braun, J. & Assessment in SpondyloArthritis international Society (ASAS) (2012). Descriptions of spinal MRI lesions and definition of a positive MRI of the spine in axial spondyloarthritis: a consensual approach by the ASAS/OMERACT MRI study group. Annals of the Rheumatic Diseases, 71(8), 1278-88. https://doi.org/10.1136/ard.2011.150680

Secher, N., Mikkelsen, M. M., Adelborg, K., Mikkelsen, R., Grove, E. L., Rubak, J. M., Vedsted, P. & Løfgren, B. (2012). Direct mail improves knowledge of basic life support guidelines in general practice: a randomised study. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 20, 72. https://doi.org/10.1186/1757-7241-20-72

Kjølby, B. F., Christensen, S., Mikkelsen, I. K., Mouridsen, K., Gall, P., Kiselev, V. & Østergaard, L. (2012). Dynamic susceptibility Contrast MRI: Compromising Perfusion Accuracy for a Better Discrimination of Hypoperfused Tissue.

Kjølby, B. F., Christensen, S., Mikkelsen, I. K., Mouridsen, K., Gall, P., Kiselev, V. & Østergaard, L. (2012). Dynamic susceptibility Contrast MRI: Improved Discrimination of Hypoperfused Tissue.

Siemonsen, S., Löbel, U., Sedlacik, J., Forkert, N. D., Mouridsen, K., Østergaard, L., Thomalla, G. & Fiehler, J. (2012). Elevated T₂-values in MRI of stroke patients shortly after symptom onset do not predict irreversible tissue infarction. Brain, 135(6), 1981-89. https://doi.org/10.1093/brain/aws079

Graumann, O., Osther, S. S. & Osther, P. J. S. (2012). Evaluering af Bosniak kategori IIf nyrecyster. http://www.drs-aarsmoede.dk/program2012.php

Nagenthiraja, K., Ribe, L. R., Hougaard, K. D., Østergaard, L. & Mouridsen, K. (2012). Fully automated DWI-PWI mismatch quantification in acute stroke. Abstract from International Society of Magnetic Resonance in Medicine 2012 , Melbourne, Australia.

Sode-Carlsen, R., Farholt, S., Rabben, K. F., Bollerslev, J., Schreiner, T., Jurik, A. G., Christiansen, J. S. & Höybye, C. (2012). Growth hormone treatment in adults with Prader-Willi syndrome - the Scandinavian study. Endocrine, 41(2), 191-199. https://doi.org/10.1007/s12020-011-9560-4

Larsen, J. K. R., Sivesgaard, K., Christensen, S. D., Hønge, J. L. & Hasenkam, M. (2012). Heart rate limitation and cardiac unloading in sevoflurane post-conditioning. Acta Anaesthesiologica Scandinavica, 56(1), 57-65. https://doi.org/10.1111/j.1399-6576.2011.02580.x

Bentzon, J. F., Sørensen, C. B., Al-Mashhadi, R. H., Kragh, P. M., Nielsen, L. B., Li, J., Lin, L., Liu, Y., Moldt, B., Schmidt, M., Thim, T., Vajta, G., Purup, S., Bolund, L., Callesen, H., Mikkelsen, J. G. & Falk, E. (2012). Hypercholesterolemic minipigs created by liver-specific expression of a PCSK9 gain-of-function mutant. Transgenic Research, 21(4), 910-911. https://doi.org/10.1007/s11248-011-9570-2

Tietze, A., Borghammer, P., Mouridsen, K., Dyve, S. & Østergaard, L. (2012). Imaging of white matter infiltration end heterogeneous histopathology in cerebral gliomas – Do [11C]-methionine Positron Emission Tomography and Perfusion-weighted Magnetic Resonance Tomography yield similar results?. Poster session presented at European Society of Neuroradiology Annual Meeting 2012, Edinburgh, United Kingdom.

Høyer, C. B., Nielsen, T. S., Nagel, L. L., Uhrenholt, L. & Boel, L. W. T. (2012). Investigation of a fatal airplane crash: autopsy, computed tomography, and injury pattern analysis used to determine who was steering the plane at time of accident. A case report. Forensic Science, Medicine, and Pathology, 8(2), 179-188. https://doi.org/10.1007/s12024-011-9239-4

Graumann, O., Osther, S. S. & Osther, P. J. S. (2012). Kan CEUS differentiere mellem benigne og maligne komplekse nyrecyster. http://www.drs-aarsmoede.dk/program2012.php

Graumann, O., Osther, S. S. & Osther, P. J. S. (2012). Kan CT-planlægningsbilledet forudsige om nyresten er røntgen-positive?. http://www.drs-aarsmoede.dk/program2012.php

Bondeven, P., Hagemann-Madsen, R. H., Bro, L., Laurberg, S. & Ginnerup, B. (2012). Length of Distal Resection Margin after Partial Mesorectal Excision for Upper Rectal Cancer Estimated by Magnetic Resonance Imaging. Abstract from PhD Day 2012, Aarhus, Denmark.

Blankholm, A. D. & Ringgaard, S. (2012). Non-contrast-enhanced magnetic resonance angiography: techniques and applications. Expert Review of Cardiovascular Therapy, 10(1), 75-88. https://doi.org/10.1586/erc.11.176

Blankholm, A. D., Ginnerup, B., Laustsen, S. & Ringgaard, S. (2012). Non-contrast enhanced MRA before kidney transplantation: A Robust Method. Poster session presented at SMRT 21st Annual Meeting, Melbourne, Australia.

Blicher, J., Stagg, C., O'Shea, J., Østergaard, L., MacIntosh, B., Johansen-Berg, H., Jezzard, P. & Donahue, M. (2012). Post-stroke fMRI, a comparison of BOLD, cerebral blood flow, and cerebral blood volume responses. Abstract from Dansk Neurologisk Selskab, Vejle, Denmark.

Lunau, L. A., Mouridsen, K., Rodell, A., Østergaard, L., Nielsen, J. E., Isaacs, A., Johannsen, P. & The FReJA Consortium (2012). Presymptomatic cerebral blood flow changes in CHMP2B mutation carriers of familial frontotemporal dementia (FTD-3), measured with MRI. BMJ Open, 2, Article e000368. https://doi.org/10.1136/bmjopen-2011-000368

Dimopoulos, J. C. A., Petrow, P., Tanderup, K., Petric, P., Berger, D., Kirisits, C., Pedersen, E. M., van Limbergen, E., Haie-Meder, C. & Pötter, R. (2012). Recommendations from Gynaecological (GYN) GEC-ESTRO Working Group (IV) - Basic principles and parameters for MR imaging within the frame of image based adaptive cervix cancer brachytherapy. Radiotherapy & Oncology. https://doi.org/10.1016/j.radonc.2011.12.024

Garza Villarreal, E. A., Brattico, E., Vase, L., Østergaard, L. & Vuust, P. (2012). Superior analgesic effect of an active distraction versus pleasant unfamiliar sounds and music: The influence of emotion and cognitive style. P L o S One, 7(1), e29397. https://doi.org/10.1371/journal.pone.0029397

Bondeven, P., Hagemann-Madsen, R. H., Bro, L., Laurberg, S. & Ginnerup, B. (2012). 'The 5 centimetre rule'. Distal Resection Margin in Cancer of the Upper Rectum Treated with Partial Mesorectal Excision. Poster session presented at PhD Day 2012, Aarhus, Denmark.

Jespersen, S. N. & Østergaard, L. (2012). The roles of cerebral blood flow, capillary transit time heterogeneity, and oxygen tension in brain oxygenation and metabolism. Journal of Cerebral Blood Flow and Metabolism, 32(2), 264-277. https://doi.org/10.1038/jcbfm.2011.153

Blicher, J., Stagg, C. J., O'Shea, J., Ostergaard, L., Macintosh, B. J., Johansen-Berg, H., Jezzard, P. & Donahue, M. J. (2012). Visualization of altered neurovascular coupling in chronic stroke patients using multimodal functional MRI. Journal of Cerebral Blood Flow and Metabolism, 32(11), 2044-2054. https://doi.org/10.1038/jcbfm.2012.105

Weber, U., Lambert, R., Rufibach , K., Maksymowych, W., Hodler, J., Zejden, A., Duewell , S., Kissling, R., Filipow, P. & Jurik, A. G. (2011). Anterior chest wall inflammation by whole body MRI in patients with spondylarthritis: frequency of involvement and association between clinical and imaging findings. Annals of the Rheumatic Diseases, 70(Suppl 3), 81.

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Rune Overgaard Jensen